The trajectory of gait speed preceding mild cognitive impairment

Teresa Buracchio, Hiroko Dodge, Diane Howieson, Dara Wasserman, Jeffrey Kaye

Research output: Contribution to journalArticle

212 Citations (Scopus)

Abstract

Objectives: To compare the trajectory of motor decline, as measured by gait speed and finger-tapping speed, between elderly people who developed mild cognitive impairment (MCI) and those who remained cognitively intact. We also sought to determine the approximate time at which the decline in motor function accelerated in persons who developed MCI. Design: Longitudinal cohort study. Participants: Participants were 204 healthy seniors (57.8% women) from the Oregon Brain Aging Study evaluated for up to 20 years using annual neurologic, neuropsychological, and motor examinations. Main Outcome Measures: The pattern of motor decline with aging was compared using amixed-effects model with an interaction term for age and a clinical diagnosis of MCI. The time before diagnosis of MCI, when the change in gait or finger-tapping speed accelerates, was assessed using a mixed-effects model with a change point for men and women, separately and combined, who developed MCI. Results: The rates of change, with aging, in gait speed (P

Original languageEnglish (US)
Pages (from-to)980-986
Number of pages7
JournalArchives of Neurology
Volume67
Issue number8
DOIs
StatePublished - Aug 2010

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Fingers
Gait
Nervous System
Longitudinal Studies
Cohort Studies
Outcome Assessment (Health Care)
Cognitive Dysfunction
Walking Speed
Trajectory
Mild Cognitive Impairment
Brain
Finger Tapping
Elderly People
Mixed Effects Model
Person
Interaction
Cohort
Change Point
Oregon

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

The trajectory of gait speed preceding mild cognitive impairment. / Buracchio, Teresa; Dodge, Hiroko; Howieson, Diane; Wasserman, Dara; Kaye, Jeffrey.

In: Archives of Neurology, Vol. 67, No. 8, 08.2010, p. 980-986.

Research output: Contribution to journalArticle

Buracchio, Teresa ; Dodge, Hiroko ; Howieson, Diane ; Wasserman, Dara ; Kaye, Jeffrey. / The trajectory of gait speed preceding mild cognitive impairment. In: Archives of Neurology. 2010 ; Vol. 67, No. 8. pp. 980-986.
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