TY - JOUR
T1 - The syndrome of inappropriate antidiuresis
AU - Ellison, David H.
AU - Berl, Tomas
PY - 2007/5/17
Y1 - 2007/5/17
N2 - A 62-year-old woman noted an unpleasant, sweet taste in her mouth. She otherwise felt well and was taking no medications. Because dysgeusia is a rare manifestation of hyponatremia, her serum sodium level was tested and was 122 mmol per liter. The serum osmolality was 250 mOsm per kilogram of water, the urinary osmolality 635 mOsm per kilogram of water, the urinary sodium 85 mmol per liter, and the urinary potassium 40 mmol per liter. Her thyroid function and adrenal function were normal. A computed tomographic (CT) scan of the thorax showed a mass in the lower lobe of the left lung, which proved to be a small-cell carcinoma. How should her hyponatremia be treated?
AB - A 62-year-old woman noted an unpleasant, sweet taste in her mouth. She otherwise felt well and was taking no medications. Because dysgeusia is a rare manifestation of hyponatremia, her serum sodium level was tested and was 122 mmol per liter. The serum osmolality was 250 mOsm per kilogram of water, the urinary osmolality 635 mOsm per kilogram of water, the urinary sodium 85 mmol per liter, and the urinary potassium 40 mmol per liter. Her thyroid function and adrenal function were normal. A computed tomographic (CT) scan of the thorax showed a mass in the lower lobe of the left lung, which proved to be a small-cell carcinoma. How should her hyponatremia be treated?
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U2 - 10.1056/NEJMcp066837
DO - 10.1056/NEJMcp066837
M3 - Article
C2 - 17507705
AN - SCOPUS:34249047454
SN - 0028-4793
VL - 356
SP - 2064
EP - 2072
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 20
ER -