The surgical management of small bowel neuroendocrine tumors

James R. Howe, Kenneth Cardona, Douglas L. Fraker, Electron Kebebew, Brian R. Untch, Yi Zarn Wang, Calvin H. Law, Eric H. Liu, Michelle K. Kim, Yusuf Menda, Brian G. Morse, Emily K. Bergsland, Jonathan R. Strosberg, Eric K. Nakakura, Rodney F. Pommier

    Research output: Contribution to journalReview article

    61 Scopus citations

    Abstract

    Small bowel neuroendocrine tumors (SBNETs) have been increasing in frequency over the past decades, and are now the most common type of small bowel tumor. Consequently, general surgeons and surgical oncologists are seeing more patients with SBNETs in their practices than ever before. The management of these patients is often complex, owing to their secretion of hormones, frequent presentation with advanced disease, and difficulties with making the diagnosis of SBNETs. Despite these issues, even patients with advanced disease can have long-Term survival. There are a number of scenarios which commonly arise in SBNET patients where it is difficult to determine the optimal management from the published data. To address these challenges for clinicians, a consensus conference was held assembling experts in the field to review and discuss the available literature and patterns of practice pertaining to specific management issues. This paper summarizes the important elements from these studies and the recommendations of the group for these questions regarding the management of SBNET patients.

    Original languageEnglish (US)
    Pages (from-to)715-731
    Number of pages17
    JournalPancreas
    Volume46
    Issue number6
    DOIs
    StatePublished - Jan 1 2017

    Keywords

    • Carcinoid tumors
    • Carcinomatosis
    • DOTATATE
    • Hepatic debulking
    • Liver metastases
    • Octreotide prophylaxis
    • Small bowel tumors
    • Unknown primary NET
    • Video capsule endoscopy

    ASJC Scopus subject areas

    • Internal Medicine
    • Endocrinology, Diabetes and Metabolism
    • Hepatology
    • Endocrinology

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  • Cite this

    Howe, J. R., Cardona, K., Fraker, D. L., Kebebew, E., Untch, B. R., Wang, Y. Z., Law, C. H., Liu, E. H., Kim, M. K., Menda, Y., Morse, B. G., Bergsland, E. K., Strosberg, J. R., Nakakura, E. K., & Pommier, R. F. (2017). The surgical management of small bowel neuroendocrine tumors. Pancreas, 46(6), 715-731. https://doi.org/10.1097/MPA.0000000000000846