The state of melanoma: challenges and opportunities

Glenn Merlino; Meenhard Herlyn; David E. Fisher; Boris C. Bastian; Keith T. Flaherty; Michael A. Davies; Jennifer A. Wargo; Clara Curiel-Lewandrowski; Michael J. Weber; Sancy A. Leachman; Maria S. Soengas; Martin McMahon; J. William Harbour; Susan M. Swetter; Andrew E. Aplin; Michael B. Atkins; Marcus W. Bosenberg; Reinhard Dummer; Jeffrey E. Gershenwald; Allan C. Halpern; Dorothee Herlyn; Giorgos C. Karakousis; John M. Kirkwood; Michael Krauthammer; Roger S. Lo; Georgina V. Long; Grant McArthur; Antoni Ribas; Lynn Schuchter; Jeffrey A. Sosman; Keiran S. Smalley; Patricia Steeg; Nancy E. Thomas; Hensin Tsao; Thomas Tueting; Ashani Weeraratna; George Xu; Randy Lomax; Alison Martin; Steve Silverstein; Tim Turnham; Ze'ev A. Ronai

doi:10.1111/pcmr.12475

The state of melanoma: challenges and opportunities

Glenn Merlino, Meenhard Herlyn, David E. Fisher, Boris C. Bastian, Keith T. Flaherty, Michael A. Davies, Jennifer A. Wargo, Clara Curiel-Lewandrowski, Michael J. Weber, Sancy A. Leachman, Maria S. Soengas, Martin McMahon, J. William Harbour, Susan M. Swetter, Andrew E. Aplin, Michael B. Atkins, Marcus W. Bosenberg, Reinhard Dummer, Jeffrey E. Gershenwald, Allan C. HalpernDorothee Herlyn, Giorgos C. Karakousis, John M. Kirkwood, Michael Krauthammer, Roger S. Lo, Georgina V. Long, Grant McArthur, Antoni Ribas, Lynn Schuchter, Jeffrey A. Sosman, Keiran S. Smalley, Patricia Steeg, Nancy E. Thomas, Hensin Tsao, Thomas Tueting, Ashani Weeraratna, George Xu, Randy Lomax, Alison Martin, Steve Silverstein, Tim Turnham, Ze'ev A. Ronai

Research output: Contribution to journal › Article › peer-review

76 Scopus citations

Abstract

The Melanoma Research Foundation (MRF) has charted a comprehensive assessment of the current state of melanoma research and care. Intensive discussions among members of the MRF Scientific Advisory Council and Breakthrough Consortium, a group that included clinicians and scientists, focused on four thematic areas – diagnosis/early detection, prevention, tumor cell dormancy (including metastasis), and therapy (response and resistance). These discussions extended over the course of 2015 and culminated at the Society of Melanoma Research 2015 International Congress in November. Each of the four groups has outlined their thoughts as per the current status, challenges, and opportunities in the four respective areas. The current state and immediate and long-term needs of the melanoma field, from basic research to clinical management, are presented in the following report.

Original language	English (US)
Pages (from-to)	404-416
Number of pages	13
Journal	Pigment Cell and Melanoma Research
Volume	29
Issue number	4
DOIs	https://doi.org/10.1111/pcmr.12475
State	Published - Jul 1 2016

Keywords

dormancy
early diagnosis
melanoma
metastasis
prevention
therapy

ASJC Scopus subject areas

Oncology
General Biochemistry, Genetics and Molecular Biology
Dermatology

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10.1111/pcmr.12475

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Merlino, G., Herlyn, M., Fisher, D. E., Bastian, B. C., Flaherty, K. T., Davies, M. A., Wargo, J. A., Curiel-Lewandrowski, C., Weber, M. J., Leachman, S. A., Soengas, M. S., McMahon, M., Harbour, J. W., Swetter, S. M., Aplin, A. E., Atkins, M. B., Bosenberg, M. W., Dummer, R., Gershenwald, J. E., ... Ronai, Z. A. (2016). The state of melanoma: challenges and opportunities. Pigment Cell and Melanoma Research, 29(4), 404-416. https://doi.org/10.1111/pcmr.12475

Merlino, G, Herlyn, M, Fisher, DE, Bastian, BC, Flaherty, KT, Davies, MA, Wargo, JA, Curiel-Lewandrowski, C, Weber, MJ, Leachman, SA, Soengas, MS, McMahon, M, Harbour, JW, Swetter, SM, Aplin, AE, Atkins, MB, Bosenberg, MW, Dummer, R, Gershenwald, JE, Halpern, AC, Herlyn, D, Karakousis, GC, Kirkwood, JM, Krauthammer, M, Lo, RS, Long, GV, McArthur, G, Ribas, A, Schuchter, L, Sosman, JA, Smalley, KS, Steeg, P, Thomas, NE, Tsao, H, Tueting, T, Weeraratna, A, Xu, G, Lomax, R, Martin, A, Silverstein, S, Turnham, T & Ronai, ZA 2016, 'The state of melanoma: challenges and opportunities', Pigment Cell and Melanoma Research, vol. 29, no. 4, pp. 404-416. https://doi.org/10.1111/pcmr.12475

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title = "The state of melanoma: challenges and opportunities",

abstract = "The Melanoma Research Foundation (MRF) has charted a comprehensive assessment of the current state of melanoma research and care. Intensive discussions among members of the MRF Scientific Advisory Council and Breakthrough Consortium, a group that included clinicians and scientists, focused on four thematic areas – diagnosis/early detection, prevention, tumor cell dormancy (including metastasis), and therapy (response and resistance). These discussions extended over the course of 2015 and culminated at the Society of Melanoma Research 2015 International Congress in November. Each of the four groups has outlined their thoughts as per the current status, challenges, and opportunities in the four respective areas. The current state and immediate and long-term needs of the melanoma field, from basic research to clinical management, are presented in the following report.",

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AU - Bastian, Boris C.

AU - Flaherty, Keith T.

AU - Davies, Michael A.

AU - Wargo, Jennifer A.

AU - Curiel-Lewandrowski, Clara

AU - Weber, Michael J.

AU - Leachman, Sancy A.

AU - Soengas, Maria S.

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AU - Gershenwald, Jeffrey E.

AU - Halpern, Allan C.

AU - Herlyn, Dorothee

AU - Karakousis, Giorgos C.

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AU - Krauthammer, Michael

AU - Lo, Roger S.

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AU - McArthur, Grant

AU - Ribas, Antoni

AU - Schuchter, Lynn

AU - Sosman, Jeffrey A.

AU - Smalley, Keiran S.

AU - Steeg, Patricia

AU - Thomas, Nancy E.

AU - Tsao, Hensin

AU - Tueting, Thomas

AU - Weeraratna, Ashani

AU - Xu, George

AU - Lomax, Randy

AU - Martin, Alison

AU - Silverstein, Steve

AU - Turnham, Tim

AU - Ronai, Ze'ev A.

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JO - Pigment Cell and Melanoma Research

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ER -

The state of melanoma: challenges and opportunities

Abstract

Keywords

ASJC Scopus subject areas

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