The Starr-Edwards model 6000 valve. A fifteen-year follow-up of the first successful mitral prosthesis

Q. Macmanus, G. Grunkemeier, Thomas Deloughery, L. E. Lambert, Albert Starr

    Research output: Contribution to journalArticle

    18 Citations (Scopus)

    Abstract

    The Starr-Edwards Model 6000 mitral valve was the first successful mitral prosthesis. A fifteen year follow-up of 110 patients undergoing isolated mitral valve replacement with this prosthesis from 1960 to 1966 is presented. There were 22 (20%) operative and 37 (42%) late deaths at a mean of 8.6 years postoperatively. Preoperative variables leading to late death and thromboembolism are analyzed. Seventeen of 25 operative survivors had improvement in their NYHA Functional Class status and eight others remained unchanged an average of 13.1 years after surgery. There are 5000 patients world-wide currently relying on this prosthesis. Despite a high rate of thromboembolism in the past, elective replacement is not recommended except in selected patients.

    Original languageEnglish (US)
    Pages (from-to)623-625
    Number of pages3
    JournalCirculation
    Volume56
    Issue number4
    StatePublished - 1977

    Fingerprint

    Prostheses and Implants
    Thromboembolism
    Mitral Valve
    Survivors

    ASJC Scopus subject areas

    • Physiology
    • Cardiology and Cardiovascular Medicine

    Cite this

    Macmanus, Q., Grunkemeier, G., Deloughery, T., Lambert, L. E., & Starr, A. (1977). The Starr-Edwards model 6000 valve. A fifteen-year follow-up of the first successful mitral prosthesis. Circulation, 56(4), 623-625.

    The Starr-Edwards model 6000 valve. A fifteen-year follow-up of the first successful mitral prosthesis. / Macmanus, Q.; Grunkemeier, G.; Deloughery, Thomas; Lambert, L. E.; Starr, Albert.

    In: Circulation, Vol. 56, No. 4, 1977, p. 623-625.

    Research output: Contribution to journalArticle

    Macmanus, Q, Grunkemeier, G, Deloughery, T, Lambert, LE & Starr, A 1977, 'The Starr-Edwards model 6000 valve. A fifteen-year follow-up of the first successful mitral prosthesis', Circulation, vol. 56, no. 4, pp. 623-625.
    Macmanus, Q. ; Grunkemeier, G. ; Deloughery, Thomas ; Lambert, L. E. ; Starr, Albert. / The Starr-Edwards model 6000 valve. A fifteen-year follow-up of the first successful mitral prosthesis. In: Circulation. 1977 ; Vol. 56, No. 4. pp. 623-625.
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    abstract = "The Starr-Edwards Model 6000 mitral valve was the first successful mitral prosthesis. A fifteen year follow-up of 110 patients undergoing isolated mitral valve replacement with this prosthesis from 1960 to 1966 is presented. There were 22 (20{\%}) operative and 37 (42{\%}) late deaths at a mean of 8.6 years postoperatively. Preoperative variables leading to late death and thromboembolism are analyzed. Seventeen of 25 operative survivors had improvement in their NYHA Functional Class status and eight others remained unchanged an average of 13.1 years after surgery. There are 5000 patients world-wide currently relying on this prosthesis. Despite a high rate of thromboembolism in the past, elective replacement is not recommended except in selected patients.",
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