The spiral ganglion: Connecting the peripheral and central auditory systems

Bryony A. Nayagam, Michael Muniak, David K. Ryugo

Research output: Contribution to journalArticle

82 Citations (Scopus)

Abstract

In mammals, the initial bridge between the physical world of sound and perception of that sound is established by neurons of the spiral ganglion. The cell bodies of these neurons give rise to peripheral processes that contact acoustic receptors in the organ of Corti, and the central processes collect together to form the auditory nerve that projects into the brain. In order to better understand hearing at this initial stage, we need to know the following about spiral ganglion neurons: (1) their cell biology including cytoplasmic, cytoskeletal, and membrane properties, (2) their peripheral and central connections including synaptic structure; (3) the nature of their neural signaling; and (4) their capacity for plasticity and rehabilitation. In this report, we will update the progress on these topics and indicate important issues still awaiting resolution.

Original languageEnglish (US)
Pages (from-to)2-20
Number of pages19
JournalHearing Research
Volume278
Issue number1-2
DOIs
StatePublished - Aug 1 2011
Externally publishedYes

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Spiral Ganglion
Neurons
Organ of Corti
Cochlear Nerve
Acoustics
Hearing
Cell Biology
Mammals
Rehabilitation
Cell Membrane
Brain

ASJC Scopus subject areas

  • Sensory Systems

Cite this

The spiral ganglion : Connecting the peripheral and central auditory systems. / Nayagam, Bryony A.; Muniak, Michael; Ryugo, David K.

In: Hearing Research, Vol. 278, No. 1-2, 01.08.2011, p. 2-20.

Research output: Contribution to journalArticle

Nayagam, Bryony A. ; Muniak, Michael ; Ryugo, David K. / The spiral ganglion : Connecting the peripheral and central auditory systems. In: Hearing Research. 2011 ; Vol. 278, No. 1-2. pp. 2-20.
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