The role of parathyroidectomy in treating hypertension and other cardiac manifestations of primary hyperparathyroidism

J. Alex Nelson, Mahmoud Alsayed, Mira Milas

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Among many recognized sequelae of primary hyperparathyroidism (PHPT), cardiovascular disease remains incompletely understood as a consequence of disordered calcium and parathyroid hormone (PTH) metabolism. While population studies have identified trends that associate PHPT with hypertension, metabolic syndrome, and vascular system calcifications, the fundamental pathophysiology, natural history, and opportunity to reverse or cure the cardiovascular effects with parathyroidectomy are not well established. This chapter reviews the current knowledge of this field of interest within PHPT and summarizes key findings from dedicated investigations that have addressed the impact of parathyroid surgery on the cardiovascular system.

Original languageEnglish (US)
Pages (from-to)136-141
Number of pages6
JournalGland Surgery
Volume9
Issue number1
DOIs
StatePublished - Feb 1 2020

Keywords

  • Cardiovascular
  • Hypertension
  • Non-dipping pattern
  • Normocalcemic
  • Parathyroidectomy
  • Primary hyperparathyroidism (PHPT)

ASJC Scopus subject areas

  • Surgery

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