The role of hemodynamic factors in the initiation and progression of renal disease

S. Anderson, T. W. Meyer, B. M. Brenner

Research output: Contribution to journalArticle

62 Scopus citations

Abstract

Hope of interrupting the progression of renal disease has stimulated investigation into the mechanism(s) responsible for the eventual destruction of remaining nephrons. Recent experimental evidence has suggested that therapeutic interventions that limit the adaptive increases in capillary pressures and flows when functioning nephron number is reduced are associated with structural preservation of the surviving nephrons.

Original languageEnglish (US)
Pages (from-to)363-368
Number of pages6
JournalJournal of Urology
Volume133
Issue number3
DOIs
StatePublished - Jan 1 1985

ASJC Scopus subject areas

  • Urology

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