The notion that oxidation of lipids and lipoproteins can contribute to the pathogenesis of atherosclerosis is supported by a large body of evidence. Furthermore, it is hypothesized that dietary antioxidants may help prevent development and progression of atherosclerosis. The available evidence supports this hypothesis, but is not yet conclusive. The results of several large ongoing randomized intervention trials will provide valuable information about the efficacy and safety of supplemental dietary antioxidants in prevention of atherosclerosis. Until the results of these trials become available, the best recommendation is to adopt a healthy life style and eat more fruits and vegetables.
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism