TY - JOUR
T1 - The role of CuCu dinuclear complexes in the oxidation of ascorbic acid by O2 a model for copper-oxidase activity
AU - Jameson, R. F.
AU - Blackburn, N. J.
PY - 1975/3
Y1 - 1975/3
N2 - The copper(II) catalysed oxidation of ascorbate by molecular oxygen has been re-investigated. The kinetics require that electron transfer from a dinuclear copper-ascorbate complex to dioxygen be invoked as the initial step in the mechanism in nitrate, fluoride and chloride media, the reaction thus being presumed to go through a higher, rather than a lower, oxidation state intermediate. The catalytic mechanism of copper-oxidases is discussed in terms of this 'model' system, the former also containing CuCu dinuclear units as oxygen binding sites.
AB - The copper(II) catalysed oxidation of ascorbate by molecular oxygen has been re-investigated. The kinetics require that electron transfer from a dinuclear copper-ascorbate complex to dioxygen be invoked as the initial step in the mechanism in nitrate, fluoride and chloride media, the reaction thus being presumed to go through a higher, rather than a lower, oxidation state intermediate. The catalytic mechanism of copper-oxidases is discussed in terms of this 'model' system, the former also containing CuCu dinuclear units as oxygen binding sites.
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U2 - 10.1016/0022-1902(75)80544-6
DO - 10.1016/0022-1902(75)80544-6
M3 - Article
AN - SCOPUS:49549138540
SN - 0022-1902
VL - 37
SP - 809
EP - 814
JO - Journal of Inorganic and Nuclear Chemistry
JF - Journal of Inorganic and Nuclear Chemistry
IS - 3
ER -