The Rise and Fall of " Biopsy and Radiate": A History of Surgical Nihilism in Glioma Treatment

Seunggu (Jude) Han, Michael E. Sughrue

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

Many neurosurgeons take a nihilistic approach to surgical treatment of gliomas, stating the inability to achieve a cure. Where this idea comes from is somewhat nebulous to most neurosurgeons. A review of the scientific studies supporting the commonly held beliefs about gliomas shows that these ideas regarding the surgical treatment of gliomas are based on overgeneralizations of data from older studies. One should avoid the temptation to apply them to the greater concept of what gliomas are, how they behave, and what should be done, but rather we should continue to scientifically evaluate the role of surgical resection in glioma treatment.

Original languageEnglish (US)
Pages (from-to)207-214
Number of pages8
JournalNeurosurgery Clinics of North America
Volume23
Issue number2
DOIs
StatePublished - Apr 1 2012
Externally publishedYes

Fingerprint

Glioma
Biopsy
Therapeutics
Neurosurgeons

Keywords

  • Glioma
  • Resection
  • Surgery

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

The Rise and Fall of " Biopsy and Radiate" : A History of Surgical Nihilism in Glioma Treatment. / Han, Seunggu (Jude); Sughrue, Michael E.

In: Neurosurgery Clinics of North America, Vol. 23, No. 2, 01.04.2012, p. 207-214.

Research output: Contribution to journalReview article

@article{0c469fa1dcd7426e815cdbcc626e9cdf,
title = "The Rise and Fall of {"} Biopsy and Radiate{"}: A History of Surgical Nihilism in Glioma Treatment",
abstract = "Many neurosurgeons take a nihilistic approach to surgical treatment of gliomas, stating the inability to achieve a cure. Where this idea comes from is somewhat nebulous to most neurosurgeons. A review of the scientific studies supporting the commonly held beliefs about gliomas shows that these ideas regarding the surgical treatment of gliomas are based on overgeneralizations of data from older studies. One should avoid the temptation to apply them to the greater concept of what gliomas are, how they behave, and what should be done, but rather we should continue to scientifically evaluate the role of surgical resection in glioma treatment.",
keywords = "Glioma, Resection, Surgery",
author = "Han, {Seunggu (Jude)} and Sughrue, {Michael E.}",
year = "2012",
month = "4",
day = "1",
doi = "10.1016/j.nec.2012.02.002",
language = "English (US)",
volume = "23",
pages = "207--214",
journal = "Neurosurgery Clinics of North America",
issn = "1042-3680",
publisher = "W.B. Saunders Ltd",
number = "2",

}

TY - JOUR

T1 - The Rise and Fall of " Biopsy and Radiate"

T2 - A History of Surgical Nihilism in Glioma Treatment

AU - Han, Seunggu (Jude)

AU - Sughrue, Michael E.

PY - 2012/4/1

Y1 - 2012/4/1

N2 - Many neurosurgeons take a nihilistic approach to surgical treatment of gliomas, stating the inability to achieve a cure. Where this idea comes from is somewhat nebulous to most neurosurgeons. A review of the scientific studies supporting the commonly held beliefs about gliomas shows that these ideas regarding the surgical treatment of gliomas are based on overgeneralizations of data from older studies. One should avoid the temptation to apply them to the greater concept of what gliomas are, how they behave, and what should be done, but rather we should continue to scientifically evaluate the role of surgical resection in glioma treatment.

AB - Many neurosurgeons take a nihilistic approach to surgical treatment of gliomas, stating the inability to achieve a cure. Where this idea comes from is somewhat nebulous to most neurosurgeons. A review of the scientific studies supporting the commonly held beliefs about gliomas shows that these ideas regarding the surgical treatment of gliomas are based on overgeneralizations of data from older studies. One should avoid the temptation to apply them to the greater concept of what gliomas are, how they behave, and what should be done, but rather we should continue to scientifically evaluate the role of surgical resection in glioma treatment.

KW - Glioma

KW - Resection

KW - Surgery

UR - http://www.scopus.com/inward/record.url?scp=84858604498&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84858604498&partnerID=8YFLogxK

U2 - 10.1016/j.nec.2012.02.002

DO - 10.1016/j.nec.2012.02.002

M3 - Review article

C2 - 22440864

AN - SCOPUS:84858604498

VL - 23

SP - 207

EP - 214

JO - Neurosurgery Clinics of North America

JF - Neurosurgery Clinics of North America

SN - 1042-3680

IS - 2

ER -