The regulation of D2 dopamine receptor expression

R. J. Hitzemann

doi:10.1038/sj.mp.4000388

The regulation of D₂ dopamine receptor expression

R. J. Hitzemann

Research output: Contribution to journal › Review article › peer-review

21 Scopus citations

Abstract

The question of whether or not there is a polymorphism in or near DRD2 which is associated with receptor density remains unanswered. Both clinical and animal data demonstrate that D₂ dopamine receptor density is highly variable among individuals; differences of more than 100% are not uncommon. Among inbred mouse strains and F₂ intercrosses produced from these strains, it appears that most of the genetic variation in receptor expression is not associated with polymorphisms in or near Drd2.

Original language	English (US)
Pages (from-to)	198-203
Number of pages	6
Journal	Molecular Psychiatry
Volume	3
Issue number	3
DOIs	https://doi.org/10.1038/sj.mp.4000388
State	Published - 1998
Externally published	Yes

ASJC Scopus subject areas

Psychiatry and Mental health
Cellular and Molecular Neuroscience
Molecular Biology

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10.1038/sj.mp.4000388

Cite this

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The regulation of D₂ dopamine receptor expression

Abstract

ASJC Scopus subject areas

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