TY - JOUR
T1 - The Prevalence of Tardive Dyskinesia in Neuroleptic-Treated Diabetics
T2 - A Controlled Study
AU - Ganzini, Linda
AU - Heintz, Ronald T.
AU - Hoffman, William F.
AU - Casey, Daniel E.
PY - 1991/3
Y1 - 1991/3
N2 - In a controlled study, we compared the prevalence of tardive dyskinesia in 38 neuroleptic-treated diabetics with the prevalence of tardive dyskinesia in a group of 38 nondiabetic neuroleptic-treated controls, matched for age, sex, psychiatric diagnosis, and dose and duration of neuroleptic treatment. Members of each group were evaluated for movement disorders by a rater who used standard rating scales and was “blind” to all diagnoses and treatments. Neuroleptic-treated diabetics had a significantly higher prevalence and severity of tardive dyskinesia. There were no differences between groups on other possible risk factors for tardive dyskinesia, including parkinsonism, anticholinergic drug treatment, or cognitive function. These data suggest that diabetes mellitus should be examined further as a risk factor for tardive dyskinesia.
AB - In a controlled study, we compared the prevalence of tardive dyskinesia in 38 neuroleptic-treated diabetics with the prevalence of tardive dyskinesia in a group of 38 nondiabetic neuroleptic-treated controls, matched for age, sex, psychiatric diagnosis, and dose and duration of neuroleptic treatment. Members of each group were evaluated for movement disorders by a rater who used standard rating scales and was “blind” to all diagnoses and treatments. Neuroleptic-treated diabetics had a significantly higher prevalence and severity of tardive dyskinesia. There were no differences between groups on other possible risk factors for tardive dyskinesia, including parkinsonism, anticholinergic drug treatment, or cognitive function. These data suggest that diabetes mellitus should be examined further as a risk factor for tardive dyskinesia.
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U2 - 10.1001/archpsyc.1991.01810270071010
DO - 10.1001/archpsyc.1991.01810270071010
M3 - Article
C2 - 1671743
AN - SCOPUS:0025980669
SN - 0003-990X
VL - 48
SP - 259
EP - 263
JO - Archives of General Psychiatry
JF - Archives of General Psychiatry
IS - 3
ER -