The clinical and laboratory features of the early stages in the evolution of acute nonlymphocytic leukemia are reviewed. Based on a retrospective analysis of 34 patients who died with an acute myelomonoblastic leukemia, the 'pre leukemic syndrome' has been shown to display a clinical picture sufficiently specific to permit its recognition prospectively (i.e., before the development of overt leukemia). The results to date of a variety of prospective studies are reviewed, and the approach(es) to the management of these cases is considered.
|Original language||English (US)|
|Number of pages||21|
|State||Published - Jan 1 1976|
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