The preleukemia syndrome: clinical and laboratory features, natural course, and management

J. W. Linman, G. C. Bagby

    Research output: Contribution to journalArticle

    109 Scopus citations

    Abstract

    The clinical and laboratory features of the early stages in the evolution of acute nonlymphocytic leukemia are reviewed. Based on a retrospective analysis of 34 patients who died with an acute myelomonoblastic leukemia, the 'pre leukemic syndrome' has been shown to display a clinical picture sufficiently specific to permit its recognition prospectively (i.e., before the development of overt leukemia). The results to date of a variety of prospective studies are reviewed, and the approach(es) to the management of these cases is considered.

    Original languageEnglish (US)
    Pages (from-to)11-31
    Number of pages21
    JournalBlood Cells
    Volume2
    Issue number1-2
    StatePublished - Jan 1 1976

    ASJC Scopus subject areas

    • Hematology

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