The Portland Neurotoxicity Scale validation of a brief self-report measure of antiepileptic-drug-related neurotoxicity

Martin Salinsky, Daniel Storzbach

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

The Portland Neurotoxicity Scale (PNS) is a brief patient-based survey of neurotoxicity complaints commonly encountered with the use of antiepileptic drugs (AEDs). The authors present data on the validity of this scale, particularly when used in longitudinal studies. Participants included 55 healthy controls, 23 epilepsy patient controls, and 86 healthy volunteers who took various AEDs or placebos for 12 weeks as part of randomized, double-blind studies of AED effects on cognitive abilities. Test-retest reliability in the control groups averaged .80 (total score). Test-retest changes in the PNS were sensitive to AED usage in general (p

Original languageEnglish (US)
Pages (from-to)107-117
Number of pages11
JournalAssessment
Volume12
Issue number1
DOIs
StatePublished - Mar 2005

Fingerprint

Anticonvulsants
Self Report
Double-Blind Method
Reproducibility of Results
Longitudinal Studies
Epilepsy
Healthy Volunteers
Placebos
Control Groups

Keywords

  • Antiepileptic drugs
  • Cognition
  • Neurotoxicity
  • Self-reporting

ASJC Scopus subject areas

  • Psychology(all)
  • Clinical Psychology

Cite this

The Portland Neurotoxicity Scale validation of a brief self-report measure of antiepileptic-drug-related neurotoxicity. / Salinsky, Martin; Storzbach, Daniel.

In: Assessment, Vol. 12, No. 1, 03.2005, p. 107-117.

Research output: Contribution to journalArticle

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