The Polyendocrine Deficiency Syndromes

D. Lynn Loriaux

Research output: Contribution to journalEditorialpeer-review

13 Scopus citations


IT is currently thought that two distinct disorders are grouped under the general rubric of polyendocrine deficiency syndrome. The first disorder begins at a mean age of about 12 years and is characterized by the association of hypoparathyroidism, primary adrenal insufficiency, and mucocutaneous candidiasis. Alopecia, pernicious anemia, malabsorption, and chronic active hepatitis also occur. This disorder is currently designated as the polyendocrine deficiency syndrome Type I.1 The inheritance pattern is not always clear, but in some families an autosomal recessive pattern has been observed.2 The second disorder begins at an average age of 30 years and is recognized by the.

Original languageEnglish (US)
Pages (from-to)1568-1569
Number of pages2
JournalNew England Journal of Medicine
Issue number24
StatePublished - Jun 13 1985
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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