TY - JOUR
T1 - The phenogen informatics website
T2 - Tools for analyses of complex traits
AU - Bhave, Sanjiv V.
AU - Hornbaker, Cheryl
AU - Phang, Tzu L.
AU - Saba, Laura
AU - Lapadat, Razvan
AU - Kechris, Katherina
AU - Gaydos, Jeanette
AU - McGoldrick, Daniel
AU - Dolbey, Andrew
AU - Leach, Sonia
AU - Soriano, Brian
AU - Ellington, Allison
AU - Ellington, Eric
AU - Jones, Kendra
AU - Mangion, Jonathan
AU - Belknap, John K.
AU - Williams, Robert W.
AU - Hunter, Lawrence E.
AU - Hoffman, Paula L.
AU - Tabakoff, Boris
PY - 2007/8/29
Y1 - 2007/8/29
N2 - Background: With the advent of "omics" (e.g. genomics, transcriptomics, proteomics and phenomics), studies can produce enormous amounts of data. Managing this diverse data and integrating with other biological data are major challenges for the bioinformatics community. Comprehensive new tools are needed to store, integrate and analyze the data efficiently. Description: The PhenoGen Informatics website http://phenogen.uchsc.edu is a comprehensive toolbox for storing, analyzing and integrating microarray data and related genotype and phenotype data. The site is particularly suited for combining QTL and microarray data to search for "candidate" genes contributing to complex traits. In addition, the site allows, if desired by the investigators, sharing of the data. Investigators can conduct "in-silico" microarray experiments using their own and/or "shared" data. Conclusion: The PhenoGen website provides access to tools that can be used for high-throughput data storage, analyses and interpretation of the results. Some of the advantages of the architecture of the website are that, in the future, the present set of tools can be adapted for the analyses of any type of high-throughput "omics" data, and that access to new tools, available in the public domain or developed at PhenoGen, can be easily provided.
AB - Background: With the advent of "omics" (e.g. genomics, transcriptomics, proteomics and phenomics), studies can produce enormous amounts of data. Managing this diverse data and integrating with other biological data are major challenges for the bioinformatics community. Comprehensive new tools are needed to store, integrate and analyze the data efficiently. Description: The PhenoGen Informatics website http://phenogen.uchsc.edu is a comprehensive toolbox for storing, analyzing and integrating microarray data and related genotype and phenotype data. The site is particularly suited for combining QTL and microarray data to search for "candidate" genes contributing to complex traits. In addition, the site allows, if desired by the investigators, sharing of the data. Investigators can conduct "in-silico" microarray experiments using their own and/or "shared" data. Conclusion: The PhenoGen website provides access to tools that can be used for high-throughput data storage, analyses and interpretation of the results. Some of the advantages of the architecture of the website are that, in the future, the present set of tools can be adapted for the analyses of any type of high-throughput "omics" data, and that access to new tools, available in the public domain or developed at PhenoGen, can be easily provided.
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U2 - 10.1186/1471-2156-8-59
DO - 10.1186/1471-2156-8-59
M3 - Article
C2 - 17760997
AN - SCOPUS:35448991344
SN - 1471-2156
VL - 8
JO - BMC Genetics
JF - BMC Genetics
M1 - 59
ER -