The optimal lipid formulation in enteral feeding in critical illness: Clinical update and review of the literature

Craig Munroe, David Frantz, Robert G. Martindale, Stephen A. McClave

Research output: Contribution to journalReview article

7 Scopus citations


Suitable and timely early enteral nutrition is paramount to providing optimal patient care for the critically ill. Lipids serve many essential roles throughout the human body, and are important components of most enteral formulations. This paper reviews lipid structure, function, and optimal utility for this macronutrient in enteral feeds. The use of omega-3 fatty acids has become common in critical care formulations, and their clinical efficacy is outlined separately. Available evidence is reviewed, and future directions are discussed.

Original languageEnglish (US)
Pages (from-to)368-375
Number of pages8
JournalCurrent gastroenterology reports
Issue number4
StatePublished - Aug 1 2011



  • ALI
  • ARDS
  • Alpha Linolenic Acid (ALA)
  • Critical illness
  • Docosahexaenoic Acid (DHA)
  • Eicosapentaenoic Acid (EPA)
  • Enteral feeding
  • Enteral nutrition
  • Essential fatty acids
  • Fish oil
  • HDL
  • LDL
  • Lipid metabolism
  • Lipids
  • Long chain fatty acids
  • Medium chain fatty acids
  • Non essential fatty acids
  • Omega 3 fatty acids
  • Omega 6 fatty acids
  • Omega 9 fatty acids
  • Optimal lipid formulation
  • Polyunsaturated fatty acids
  • Saturated fatty acids
  • Short chain fatty acids
  • Structured lipids
  • Triglycerides
  • Unsaturated fatty acids
  • VLDL

ASJC Scopus subject areas

  • Gastroenterology

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