The mRDH bandage provides effective hemostasis in trauma and surgical hemorrhage

David R. King, Martin Schreiber

    Research output: Contribution to journalArticle

    8 Citations (Scopus)

    Abstract

    Background: Traumatic injury is a major global health problem, accounting for approximately 1 in 10 deaths worldwide. Hemorrhagic shock accounts for 30% to 40% of injury-associated deaths (2/3 of those patients surviving to reach the hospital) and is the leading cause of preventable and early in-hospital mortality. Excessive blood loss is an infrequent but important complication of both elective and emergency surgery, increasing the risk of morbidity and mortality and prolonging the duration of hospital stay. Results: The modified rapid deployment hemostat (mRDH) trauma bandage has been developed and tested during the past several years. The mRDH has a unique mechanism of action involving vasoconstriction, platelet activation, and red blood cell activation and is effective in the absence of clotting factors or platelets. The mRDH bandage has shown hemostatic efficacy in patients with severe visceral injuries and hepatic rupture. Conclusions: The following case studies illustrate the effective use of the mRDH bandage in a variety of settings, as follows: (1) application of the mRDH to control severe hemorrhage from an improvised explosive deviceinduced lower extremity injury in Iraq and (2) the mRDH terminates bleeding from a penetrating groin wound allowing safe neurosurgical intervention while avoiding a groin exploration.

    Original languageEnglish (US)
    JournalJournal of Trauma - Injury, Infection and Critical Care
    Volume71
    Issue number2 SUPPL. 1
    DOIs
    StatePublished - Aug 2011

    Fingerprint

    Surgical Blood Loss
    Bandages
    Hemostasis
    Wounds and Injuries
    Groin
    Hemorrhage
    Penetrating Wounds
    Iraq
    Blood Coagulation Factors
    Hemorrhagic Shock
    Platelet Activation
    Hemostatics
    Hospital Mortality
    Vasoconstriction
    Rupture
    Lower Extremity
    Length of Stay
    Emergencies
    Blood Platelets
    Erythrocytes

    Keywords

    • Battlefield wounds
    • Hemorrhage
    • Hemostasis
    • MRDH bandage
    • Surgery
    • Trauma

    ASJC Scopus subject areas

    • Surgery
    • Critical Care and Intensive Care Medicine

    Cite this

    The mRDH bandage provides effective hemostasis in trauma and surgical hemorrhage. / King, David R.; Schreiber, Martin.

    In: Journal of Trauma - Injury, Infection and Critical Care, Vol. 71, No. 2 SUPPL. 1, 08.2011.

    Research output: Contribution to journalArticle

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