The membrane proximal region of the cannabinoid receptor CB₁ N-terminus can allosterically modulate ligand affinity

Medicine & Life Sciences

• Cannabinoid Receptor CB1 100%
• Disulfides 69%
• Ligands 55%
• Membranes 46%
• 1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea 28%
• Cysteine 24%
• Reducing Agents 16%
• G-Protein-Coupled Receptors 13%
• Binding Sites 10%
• Mutation 7%

Chemical Compounds

• Cannabinoid 99%
• Disulfide 64%
• Ligand 34%
• Cysteine Residue 16%
• Reducing Agent 13%
• Cysteine 13%
• Mutation 13%
• Binding Site 11%