The lymphocytic cathepsins B-1 and D activities in multiple sclerosis

K. R. Govindarajan, Halina Offner, J. Clausen, T. Fog, K. Hyllested

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Cathepsin B-1 and D activity in lymphocytes obtained from 25 multiple sclerosis (MS) patients with various degrees of disability due to the disease and from a similar number of control subjects were studied. No differences were found between the enzyme activities of cells obtained from MS patients and controls. Age, sex and the degree of disability in the patients at the time of testing did not correlate with the enzyme activities found. The results from the present study are discussed in relation to the probable role played by lymphocytes in the demyelination process.

Original languageEnglish (US)
Pages (from-to)81-87
Number of pages7
JournalJournal of the Neurological Sciences
Volume23
Issue number1
DOIs
StatePublished - 1974
Externally publishedYes

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Cathepsin B
Cathepsin D
Multiple Sclerosis
Lymphocytes
Demyelinating Diseases
Enzymes

ASJC Scopus subject areas

  • Aging
  • Clinical Neurology
  • Surgery
  • Neuroscience(all)
  • Developmental Neuroscience
  • Neurology

Cite this

The lymphocytic cathepsins B-1 and D activities in multiple sclerosis. / Govindarajan, K. R.; Offner, Halina; Clausen, J.; Fog, T.; Hyllested, K.

In: Journal of the Neurological Sciences, Vol. 23, No. 1, 1974, p. 81-87.

Research output: Contribution to journalArticle

Govindarajan, K. R. ; Offner, Halina ; Clausen, J. ; Fog, T. ; Hyllested, K. / The lymphocytic cathepsins B-1 and D activities in multiple sclerosis. In: Journal of the Neurological Sciences. 1974 ; Vol. 23, No. 1. pp. 81-87.
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