The Life of a Fracture: Biologic Progression, Healing Gone Awry, and Evaluation of Union

Justin E. Hellwinkel, Theodore Miclau, Matthew T. Provencher, Chelsea S. Bahney, Zachary M. Working

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations

Abstract

New knowledge about the molecular biology of fracture-healing provides opportunities for intervention and reduction of risk for specific phases that are affected by disease and medications. Modifiable and nonmodifiable risk factors can prolong healing, and the informed clinician should optimize each patient to provide the best chance for union. Techniques to monitor progression of fracture-healing have not changed substantially over time; new objective modalities are needed.

Original languageEnglish (US)
Pages (from-to)e1900221
JournalJBJS Reviews
Volume8
Issue number8
DOIs
StatePublished - Aug 1 2020

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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