The isolation and structure of modified bio active nucleosides from jaspis johnstoni

T. Mark Zabriskie, Chris M. Ireland

Research output: Contribution to journalArticle

27 Scopus citations


Two cytotoxic pyrrolo[ 2,3-d]pyrimidine nucleosides, toyocamycin [2] and 5-(methoxycarbonyl)tubercidin [1], have been isolated from the Fijian spongeJaspis johnstoni. The structures were solved primarily by13C nmr and mass spectral methods and confirmed by comparison to reported values in the literature. Small amounts of the corresponding aglycones were also isolated.

Original languageEnglish (US)
Pages (from-to)1353-1356
Number of pages4
JournalJournal of Natural Products
Issue number6
StatePublished - Nov 1 1989


ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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