The internal circadian clock increases hunger and appetite in the evening independent of food intake and other behaviors

Frank A J L Scheer, Christopher J. Morris, Steven Shea

Research output: Contribution to journalArticle

76 Citations (Scopus)

Abstract

Objective: Despite the extended overnight fast, paradoxically, people are typically not ravenous in the morning and breakfast is typically the smallest meal of the day. We assessed whether this paradox could be explained by an endogenous circadian influence on appetite with a morning trough, while controlling for sleep/wake and fasting/feeding effects. Design and Methods: Twelve healthy non-obese adults (six males; age, 20-42 years) were studied throughout a 13-day laboratory protocol that balanced all behaviors, including eucaloric meals and sleep periods, evenly across the endogenous circadian cycle. Participants rated their appetite and food preferences by visual analog scales. Results: There was a large endogenous circadian rhythm in hunger, with the trough in the biological morning (8 AM) and peak in the biological evening (8 PM; peak-to-trough amplitude = 17%; P = 0.004). Similarly-phased significant endogenous circadian rhythms were present in appetites for sweet, salty and starchy foods, fruits, meats/poultry, food overall, and for estimates of how much food participants could eat (amplitudes 14-25%; all P <0.05). Conclusions: In people who sleep at night, the intrinsic circadian evening peak in appetite may promote larger meals before the fasting period necessitated by sleep, whereas the circadian morning trough would theoretically facilitate the extended overnight fast. Furthermore, the circadian decline in hunger across the night would theoretically counteract the fasting-induced hunger increase that could otherwise disrupt sleep.

Original languageEnglish (US)
Pages (from-to)421-423
Number of pages3
JournalObesity
Volume21
Issue number3
DOIs
StatePublished - Mar 2013

Fingerprint

Circadian Clocks
Hunger
Appetite
Sleep
Eating
Meals
Fasting
Circadian Rhythm
Food
Food Preferences
Breakfast
Poultry
Visual Analog Scale
Meat
Fruit

ASJC Scopus subject areas

  • Endocrinology
  • Medicine (miscellaneous)
  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics

Cite this

The internal circadian clock increases hunger and appetite in the evening independent of food intake and other behaviors. / Scheer, Frank A J L; Morris, Christopher J.; Shea, Steven.

In: Obesity, Vol. 21, No. 3, 03.2013, p. 421-423.

Research output: Contribution to journalArticle

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