The induction of oral ethanol self-administration by contingent ethanol delivery

Kathleen A. Grant, Herman H. Samson

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


The necessity of delivering a highly reinforcing stimulus (20% sucrose) contingent upon ethanol consumption in order to induce ethanol self-administration in free-feeding rats was investigated. Rats water deprived for 12-16 h were placed in an environment in which ethanol drinking resulted in the presentation of ethanol. This procedure was successful in inducing and maintaining ethanol self-administration over concentrations of 5-20% (v/v). Compared to a group of rats initially reinforced for drinking ethanol with sucrose presentation, contingent ethanol delivery resulted in greater ethanol self-administration behavior. When 20% ethanol was available the group trained with ethanol had average intake of 0.91 g/kg, whereas the group trained with sucrose had a mean intake of 0.69 g/kg in a 30-min session. The results suggest that ethanol's reinforcing properties are sufficient to establish ethanol self-administration within the context of the inducing environment.

Original languageEnglish (US)
Pages (from-to)361-368
Number of pages8
JournalDrug and Alcohol Dependence
Issue number4
StatePublished - Feb 1986
Externally publishedYes


  • Alcohol
  • Alcohol self-administration
  • Rats
  • Reinforcement

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology
  • Psychiatry and Mental health
  • Pharmacology (medical)


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