The impact of the use of the isolated echogenic intracardiac focus as a screen for Down syndrome in women under the age of 35 years

Aaron Caughey, Deirdre J. Lyell, Roy A. Filly, A. Eugene Washington, Mary E. Norton

Research output: Contribution to journalArticle

22 Scopus citations


OBJECTIVE: The purpose of this study was to determine the public health impact of the routine offering of amniocentesis to women under the age of 35 years who have an isolated fetal echogenic intracardiac focus on second trimester ultrasound scan. STUDY DESIGN: A decision analytic model was designed that compared the accepted standard of second trimester triple marker screen for Down syndrome to a policy in which amniocentesis with an isolated echogenic intracardiac focus on ultrasound in addition to the triple marker screen is offered to all women in the United States who are

Original languageEnglish (US)
Pages (from-to)1021-1027
Number of pages7
JournalAmerican Journal of Obstetrics and Gynecology
Issue number5
Publication statusPublished - 2001
Externally publishedYes



  • Down syndrome
  • Echogenic intracardiac focus
  • Prenatal testing
  • Ultrasound

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

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