The immune consequences of trauma

S. E. Miller, C. L. Miller, Donald Trunkey

Research output: Contribution to journalArticle

77 Citations (Scopus)

Abstract

Numerous studies have documented the role of trauma in adversely modifying host defense mechanisms. A major objective of current investigations is to delineate the mechanisms of trauma-mediated depression of host defense and to define the relationship of such depression to susceptibility to fatal septicemia following trauma. The purpose of this article is to provide an overview of current knowledge of trauma-mediated alterations of host defense mechanisms. Although not discussed in this review, a variety of treatment modalities utilized in the care of traumatized patients have also been shown to depress host defense mechanisms. Such modalities include antibiotics, steroids, and anesthetic agents.

Original languageEnglish (US)
Pages (from-to)167-181
Number of pages15
JournalSurgical Clinics of North America
Volume62
Issue number1
StatePublished - 1982
Externally publishedYes

Fingerprint

Wounds and Injuries
Anesthetics
Sepsis
Patient Care
Steroids
Anti-Bacterial Agents
Therapeutics

ASJC Scopus subject areas

  • Surgery

Cite this

Miller, S. E., Miller, C. L., & Trunkey, D. (1982). The immune consequences of trauma. Surgical Clinics of North America, 62(1), 167-181.

The immune consequences of trauma. / Miller, S. E.; Miller, C. L.; Trunkey, Donald.

In: Surgical Clinics of North America, Vol. 62, No. 1, 1982, p. 167-181.

Research output: Contribution to journalArticle

Miller, SE, Miller, CL & Trunkey, D 1982, 'The immune consequences of trauma', Surgical Clinics of North America, vol. 62, no. 1, pp. 167-181.
Miller, S. E. ; Miller, C. L. ; Trunkey, Donald. / The immune consequences of trauma. In: Surgical Clinics of North America. 1982 ; Vol. 62, No. 1. pp. 167-181.
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