TY - JOUR
T1 - The human gene for the β subunit of nerve growth factor is located on the proximal short arm of chromosome 1
AU - Francke, Uta
AU - De Martinville, Bérengére
AU - Coussens, Lisa
AU - Ullrich, Axel
PY - 1983
Y1 - 1983
N2 - Fragments of the recently cloned human gene for the β subunit of nerve growth factor (β-NGF) were used as hybridization probes in analyzing two sets of rodent-human somatic cell hybrids for the presence of human β-NGF sequences. Results from the first set of hybrids assigned the human β-NGF gene to chromosome 1 and ruled out the presence of sequences of comparable homology on any other chromosome. With the second set of hybrids, which contained seven different, but overlapping, regions of chromosome 1, the NGF locus was mapped to band 1p22.
AB - Fragments of the recently cloned human gene for the β subunit of nerve growth factor (β-NGF) were used as hybridization probes in analyzing two sets of rodent-human somatic cell hybrids for the presence of human β-NGF sequences. Results from the first set of hybrids assigned the human β-NGF gene to chromosome 1 and ruled out the presence of sequences of comparable homology on any other chromosome. With the second set of hybrids, which contained seven different, but overlapping, regions of chromosome 1, the NGF locus was mapped to band 1p22.
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U2 - 10.1126/science.6648531
DO - 10.1126/science.6648531
M3 - Article
C2 - 6648531
AN - SCOPUS:0021012836
SN - 0036-8075
VL - 222
SP - 1248
EP - 1251
JO - Science
JF - Science
IS - 4629
ER -