The Harmonizing Outcome Measures for Eczema (HOME) Roadmap

A Methodological Framework to Develop Core Sets of Outcome Measurements in Dermatology

Jochen Schmitt, Christian Apfelbacher, Phyllis I. Spuls, Kim S. Thomas, Eric Simpson, Masutaka Furue, Joanne Chalmers, Hywel C. Williams

Research output: Contribution to journalArticle

97 Citations (Scopus)

Abstract

Core outcome sets (COSs) are consensus-derived minimum sets of outcomes to be assessed in a specific situation. COSs are being increasingly developed to limit outcome-reporting bias, allow comparisons across trials, and strengthen clinical decision making. Despite the increasing interest in outcomes research, methods to develop COSs have not yet been standardized. The aim of this paper is to present the Harmonizing Outcomes Measures for Eczema (HOME) roadmap for the development and implementation of COSs, which was developed on the basis of our experience in the standardization of outcome measurements for atopic eczema. Following the establishment of a panel representing all relevant stakeholders and a research team experienced in outcomes research, the scope and setting of the core set should be defined. The next steps are the definition of a core set of outcome domains such as symptoms or quality of life, followed by the identification or development and validation of appropriate outcome measurement instruments to measure these core domains. Finally, the consented COS needs to be disseminated, implemented, and reviewed. We believe that the HOME roadmap is a useful methodological framework to develop COSs in dermatology, with the ultimate goal of better decision making and promoting patient-centered health care.

Original languageEnglish (US)
Pages (from-to)24-30
Number of pages7
JournalJournal of Investigative Dermatology
Volume135
Issue number1
DOIs
StatePublished - Jan 1 2015

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Dermatology
Eczema
Outcome Assessment (Health Care)
Decision making
Health care
Patient-Centered Care
Standardization
Atopic Dermatitis
Consensus
Decision Making
Quality of Life
Delivery of Health Care
Research

ASJC Scopus subject areas

  • Dermatology
  • Biochemistry
  • Cell Biology
  • Molecular Biology

Cite this

The Harmonizing Outcome Measures for Eczema (HOME) Roadmap : A Methodological Framework to Develop Core Sets of Outcome Measurements in Dermatology. / Schmitt, Jochen; Apfelbacher, Christian; Spuls, Phyllis I.; Thomas, Kim S.; Simpson, Eric; Furue, Masutaka; Chalmers, Joanne; Williams, Hywel C.

In: Journal of Investigative Dermatology, Vol. 135, No. 1, 01.01.2015, p. 24-30.

Research output: Contribution to journalArticle

Schmitt, Jochen ; Apfelbacher, Christian ; Spuls, Phyllis I. ; Thomas, Kim S. ; Simpson, Eric ; Furue, Masutaka ; Chalmers, Joanne ; Williams, Hywel C. / The Harmonizing Outcome Measures for Eczema (HOME) Roadmap : A Methodological Framework to Develop Core Sets of Outcome Measurements in Dermatology. In: Journal of Investigative Dermatology. 2015 ; Vol. 135, No. 1. pp. 24-30.
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