The genetics of hearing and balance in zebrafish

Teresa Nicolson

doi:10.1146/annurev.genet.39.073003.105049

The genetics of hearing and balance in zebrafish

Teresa Nicolson

Otolaryngology

Research output: Contribution to journal › Review article › peer-review

203 Scopus citations

Abstract

The zebrafish is an excellent model system for studying the molecular basis of inner ear development and function. The eggs develop ex utero and the ear is transparent for the first few weeks of life. Forward genetic screens and antisense technology have helped to elucidate the signaling pathways and molecules required for inner ear development and function. This review addresses the most recent advances in our understanding of how the ear forms and discusses the molecules in hair cells that are essential for sensing sound and movement in the zebrafish.

Original language	English (US)
Pages (from-to)	9-22
Number of pages	14
Journal	Annual Review of Genetics
Volume	39
DOIs	https://doi.org/10.1146/annurev.genet.39.073003.105049
State	Published - 2005

Keywords

Deafness
Development
Hair cells
Inner ear
Lateral line organ
Mechanotransduction

ASJC Scopus subject areas

Genetics

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10.1146/annurev.genet.39.073003.105049

Cite this

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KW - Lateral line organ

KW - Mechanotransduction

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The genetics of hearing and balance in zebrafish

Abstract

Keywords

ASJC Scopus subject areas

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