The futility of hemoperfusion and hemodialysis in Amanita phalloides poisoning

Michael E. Mullins, B (Zane) Horowitz

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Amanita phalloides mushrooms are extremely toxic. A variety of treatments have been proposed based as often on anecdotal experience as on firm evidence. General consensus exists regarding some treatments, such as the use of silibinin, penicillin, and activated charcoal. The most polarized debate concerns the value of extracorporeal elimination. We describe a case of 2 adults with confirmed Amanita phalloides poisoning treated with hemodialysis (HD) immediately after arrival at our tertiary care hospital (23 h after ingestion) and later with hemoperfusion (HP); a series blood samples were taken to determine the clearance of the toxin by each method. No amatoxin was detected before treatment, after treatment, or in the HD/HP circuits. Neither HD nor HP contributed to the clearance of amatoxin.

Original languageEnglish (US)
Pages (from-to)90-91
Number of pages2
JournalVeterinary and Human Toxicology
Volume42
Issue number2
StatePublished - Apr 2000
Externally publishedYes

Fingerprint

Amanita phalloides
Amanita
Medical Futility
Hemoperfusion
hemodialysis
amanitins
Poisoning
Renal Dialysis
poisoning
Poisons
Charcoal
Penicillins
Blood
penicillins
activated carbon
mushrooms
Networks (circuits)
Agaricales
toxins
Tertiary Healthcare

ASJC Scopus subject areas

  • veterinary(all)
  • Toxicology
  • Health, Toxicology and Mutagenesis

Cite this

The futility of hemoperfusion and hemodialysis in Amanita phalloides poisoning. / Mullins, Michael E.; Horowitz, B (Zane).

In: Veterinary and Human Toxicology, Vol. 42, No. 2, 04.2000, p. 90-91.

Research output: Contribution to journalArticle

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