The exciting origin of guinea-pig inferior mesenteric ganglion neurons in vivo

Ming Yi Shi, Hua Zhu Zhou, Zhi Gen Jiang

Research output: Contribution to journalArticle

Abstract

Intracellular recording in vivo showed that spontaneous activities of guinea-pig inferior mesenteric ganglion (IMG) neurons were inhibited when any one of the four groups of the nerves connected to the IMG was cutted or blocked, indicating that all the four groups of nerves sent in excitatory input. Colonic and hypogastric nerves convey the peripheral excitation respectively from colon and bladder. Intermesenteric nerve sends in peripheral excitatory input from colon and central from spinal cord. This finding suggests that the excitation of the prevertebral ganglia originates from not only spinal cord as claimed tranditionally, but also the peripheral organs. The latter exits stronger effect than the former. It seems that IMG is an integration neurocenter rather than a simple signal relay station from the central nervous system to peripheral effectors.

Original languageEnglish (US)
Pages (from-to)301-304
Number of pages4
JournalActa Physiologica Sinica
Volume48
Issue number3
StatePublished - Jan 1 1996

Keywords

  • Bladder
  • Colon
  • In vivo
  • Sympathetic ganglion
  • Synaptic potential

ASJC Scopus subject areas

  • Medicine(all)

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    Shi, M. Y., Zhou, H. Z., & Jiang, Z. G. (1996). The exciting origin of guinea-pig inferior mesenteric ganglion neurons in vivo. Acta Physiologica Sinica, 48(3), 301-304.