The examination of isolated nerve fibres by light and electron microscopy, with observations on demyelination proximal to neuromas

Peter S. Spencer; P. K. Thomas

doi:10.1007/BF00687357

The examination of isolated nerve fibres by light and electron microscopy, with observations on demyelination proximal to neuromas

Peter S. Spencer, P. K. Thomas

Research output: Contribution to journal › Article › peer-review

102 Scopus citations

Abstract

A technique is described for isolating peripheral nerve fibres by teasing and subsequently examining them by light and electron microscopy. The technique was applied to the study of unusual swollen fibres observed central to the lesion in transected nerves in rats. These were shown to be the result of the demyelination of already remyelinated segments of the fibre.

Original language	English (US)
Pages (from-to)	177-186
Number of pages	10
Journal	Acta Neuropathologica
Volume	16
Issue number	3
DOIs	https://doi.org/10.1007/BF00687357
State	Published - Sep 1970
Externally published	Yes

Keywords

Demyelination
Electron Microscopy
Isolated Nerve Fibres

ASJC Scopus subject areas

Pathology and Forensic Medicine
Clinical Neurology
Cellular and Molecular Neuroscience

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10.1007/BF00687357

Cite this

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title = "The examination of isolated nerve fibres by light and electron microscopy, with observations on demyelination proximal to neuromas",

abstract = "A technique is described for isolating peripheral nerve fibres by teasing and subsequently examining them by light and electron microscopy. The technique was applied to the study of unusual swollen fibres observed central to the lesion in transected nerves in rats. These were shown to be the result of the demyelination of already remyelinated segments of the fibre.",

keywords = "Demyelination, Electron Microscopy, Isolated Nerve Fibres",

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year = "1970",

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AU - Thomas, P. K.

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N2 - A technique is described for isolating peripheral nerve fibres by teasing and subsequently examining them by light and electron microscopy. The technique was applied to the study of unusual swollen fibres observed central to the lesion in transected nerves in rats. These were shown to be the result of the demyelination of already remyelinated segments of the fibre.

AB - A technique is described for isolating peripheral nerve fibres by teasing and subsequently examining them by light and electron microscopy. The technique was applied to the study of unusual swollen fibres observed central to the lesion in transected nerves in rats. These were shown to be the result of the demyelination of already remyelinated segments of the fibre.

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KW - Electron Microscopy

KW - Isolated Nerve Fibres

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The examination of isolated nerve fibres by light and electron microscopy, with observations on demyelination proximal to neuromas

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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