The examination of isolated nerve fibres by light and electron microscopy, with observations on demyelination proximal to neuromas

Peter S. Spencer, P. K. Thomas

Research output: Contribution to journalArticle

99 Scopus citations

Abstract

A technique is described for isolating peripheral nerve fibres by teasing and subsequently examining them by light and electron microscopy. The technique was applied to the study of unusual swollen fibres observed central to the lesion in transected nerves in rats. These were shown to be the result of the demyelination of already remyelinated segments of the fibre.

Original languageEnglish (US)
Pages (from-to)177-186
Number of pages10
JournalActa Neuropathologica
Volume16
Issue number3
DOIs
StatePublished - Sep 1970

Keywords

  • Demyelination
  • Electron Microscopy
  • Isolated Nerve Fibres

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Clinical Neurology
  • Cellular and Molecular Neuroscience

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