The examination of isolated nerve fibres by light and electron microscopy, with observations on demyelination proximal to neuromas

Peter S. Spencer, P. K. Thomas

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99 Scopus citations


A technique is described for isolating peripheral nerve fibres by teasing and subsequently examining them by light and electron microscopy. The technique was applied to the study of unusual swollen fibres observed central to the lesion in transected nerves in rats. These were shown to be the result of the demyelination of already remyelinated segments of the fibre.

Original languageEnglish (US)
Pages (from-to)177-186
Number of pages10
JournalActa Neuropathologica
Issue number3
StatePublished - Sep 1 1970



  • Demyelination
  • Electron Microscopy
  • Isolated Nerve Fibres

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Clinical Neurology
  • Cellular and Molecular Neuroscience

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