@article{999ad8f1e9ad4420ba8d8670e0c7bd7d,
title = "The effects of pre-enucleation irradiation on the development of metastases from intraocular greene melanoma in hamsters",
abstract = "Using intraocular Greene melanoma in a hamster model, we studied the effect of pre-enucleation irradiation on the development of melanoma metastases. One group (No. = 111) was treated with 1,210 to 1,600 rads of cobaltous chloride Co 60 gamma irradiation before enucleation and the second group (No. = 100) received no irradiation. The groups did not differ with respect to presence of metastases in the 106 days after tumor implantation (χ2 = 3.05; P = .08). However, Kaplan-Meier survival curves gave a longer time to melanoma-related death in the irradiated animals compared with the controls (log rank test, P = .0008).",
author = "Fournier, {George A.} and Saulenas, {Amanda M.} and Seddon, {Johanna M.} and Michael Goitein and Albert, {Daniel M.} and Lela Polivogianis and Evangelos Gragoudas",
note = "Funding Information: Accepted for publication Aug. 9, 1985. From the Department of Ophthalmology, Massachusetts Eye and Ear Infirmary (Drs. Fournier, Seddon, Albert, and Gragoudas, Ms. Saulenas, and Ms. Polivogianis), and the Department of Radiation Medicine, Massachusetts General Hospital Cancer Center and Harvard Medical School (Dr. Goitein), Boston, Massachusetts. This study was supported in part by grant EY01917 from the National Institutes of Health. Reprint requests to Daniel M. Albert, M.D., Massachusetts Eye and Ear Infirmary, 243 Charles St., Boston, MA 02114.",
year = "1985",
month = nov,
day = "15",
doi = "10.1016/0002-9394(85)90622-1",
language = "English (US)",
volume = "100",
pages = "669--677",
journal = "American journal of ophthalmology",
issn = "0002-9394",
publisher = "Elsevier USA",
number = "5",
}