The effect of dietary glutamate on fibromyalgia and irritable bowel symptoms

Kathleen F. Holton, Douglas L. Taren, Cynthia A. Thomson, Robert (Rob) Bennett, Kim Jones

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Objective: To examine the effects of a challenge with monosodium glutamate (MSG) as compared to placebo on the symptoms of fibromyalgia (FM), in participants who initially experienced 0.02); a worsening of fibromyalgia severity as determined by the FIQR (p>0.03); decreased quality of life in regards to IBS symptoms (IBS QOL, p>0.05); and a non-significant trend toward worsening FM pain based on visual analogue scale (VAS, p>0.07). Conclusion: These findings suggest that dietary glutamate may be contributing to FM symptoms in some patients. Future research on the role of dietary excitotoxins in FM is warranted.

Original languageEnglish (US)
JournalClinical and Experimental Rheumatology
Volume30
Issue numberSUPPL.74
StatePublished - 2012

Fingerprint

Fibromyalgia
Glutamic Acid
Sodium Glutamate
Neurotoxins
Visual Analog Scale
Placebos
Quality of Life
Pain

Keywords

  • Adverse effects
  • Diet
  • Fibromyalgia
  • Glutamate
  • Irritable bowel syndrome

ASJC Scopus subject areas

  • Rheumatology
  • Immunology
  • Immunology and Allergy

Cite this

Holton, K. F., Taren, D. L., Thomson, C. A., Bennett, R. R., & Jones, K. (2012). The effect of dietary glutamate on fibromyalgia and irritable bowel symptoms. Clinical and Experimental Rheumatology, 30(SUPPL.74).

The effect of dietary glutamate on fibromyalgia and irritable bowel symptoms. / Holton, Kathleen F.; Taren, Douglas L.; Thomson, Cynthia A.; Bennett, Robert (Rob); Jones, Kim.

In: Clinical and Experimental Rheumatology, Vol. 30, No. SUPPL.74, 2012.

Research output: Contribution to journalArticle

Holton, KF, Taren, DL, Thomson, CA, Bennett, RR & Jones, K 2012, 'The effect of dietary glutamate on fibromyalgia and irritable bowel symptoms', Clinical and Experimental Rheumatology, vol. 30, no. SUPPL.74.
Holton KF, Taren DL, Thomson CA, Bennett RR, Jones K. The effect of dietary glutamate on fibromyalgia and irritable bowel symptoms. Clinical and Experimental Rheumatology. 2012;30(SUPPL.74).
Holton, Kathleen F. ; Taren, Douglas L. ; Thomson, Cynthia A. ; Bennett, Robert (Rob) ; Jones, Kim. / The effect of dietary glutamate on fibromyalgia and irritable bowel symptoms. In: Clinical and Experimental Rheumatology. 2012 ; Vol. 30, No. SUPPL.74.
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