The durability of Laparoscopic Nissen fundoplication: 11-year outcomes

Craig B. Morgenthal, Matthew D. Shane, Alessandro Stival, Nana Gletsu, Graham Milam, Vickie Swafford, John Hunter, C. Daniel Smith

Research output: Contribution to journalArticle

61 Scopus citations


Laparoscopic Nissen fundoplication (LNF) has become the most commonly performed antireflux procedure since its introduction in 1991. There are few studies with greater than 5-year outcomes. Herein we report a series of 312 consecutive patients who underwent primary LNF before 1996. Follow-up of more than 6 years was available in 166 patients, and the mean follow-up was 11 years (median 11.1 years, range 6.1-13.3 years). Prospective data collection included preoperative and current symptom scores (scale 0∈=∈none to 3∈=∈severe), as well as the level of patient satisfaction and use of antireflux medications. Total symptom score for each patient was summed from seven symptoms for a maximum value of 21. Heartburn and regurgitation were the most improved symptoms; however, all symptoms were significantly improved (P∈

Original languageEnglish (US)
Pages (from-to)693-700
Number of pages8
JournalJournal of Gastrointestinal Surgery
Issue number6
Publication statusPublished - Jun 2007


  • Antireflux surgery
  • GERD
  • Laparoscopic Nissen fundoplication
  • Long-term outcomes

ASJC Scopus subject areas

  • Surgery

Cite this

Morgenthal, CB, Shane, MD, Stival, A, Gletsu, N, Milam, G, Swafford, V, Hunter, J & Smith, CD 2007, 'The durability of Laparoscopic Nissen fundoplication: 11-year outcomes', Journal of Gastrointestinal Surgery, vol. 11, no. 6, pp. 693-700.