TY - JOUR
T1 - The complete genome of Teredinibacter turnerae T7901
T2 - An intracellular endosymbiont of marine wood-boring bivalves (shipworms)
AU - Yang, Joyce C.
AU - Madupu, Ramana
AU - Durkin, A. Scott
AU - Ekborg, Nathan A.
AU - Pedamallu, Chandra S.
AU - Hostetler, Jessica B.
AU - Radune, Diana
AU - Toms, Bradley S.
AU - Henrissat, Bernard
AU - Coutinho, Pedro M.
AU - Schwarz, Sandra
AU - Field, Lauren
AU - Trindade-Silva, Amaro E.
AU - Soares, Carlos A.G.
AU - Elshahawi, Sherif
AU - Hanora, Amro
AU - Schmidt, Eric W.
AU - Haygood, Margo G.
AU - Posfai, Janos
AU - Benner, Jack
AU - Madinger, Catherine
AU - Nove, John
AU - Anton, Brian
AU - Chaudhary, Kshitiz
AU - Foster, Jeremy
AU - Holman, Alex
AU - Kumar, Sanjay
AU - Lessard, Philip A.
AU - Luyten, Yvette A.
AU - Slatko, Barton
AU - Wood, Nicole
AU - Wu, Bo
AU - Teplitski, Max
AU - Mougous, Joseph D.
AU - Ward, Naomi
AU - Eisen, Jonathan A.
AU - Badger, Jonathan H.
AU - Distel, Daniel L.
PY - 2009/7/1
Y1 - 2009/7/1
N2 - Here we report the complete genome sequence of Teredinibacter turnerae T7901. T. turnerae is a marine gamma proteobacterium that occurs as an intracellular endosymbiont in the gills of wood-boring marine bivalves of the family Teredinidae (shipworms). This species is the sole cultivated member of an endosymbiotic consortium thought to provide the host with enzymes, including cellulases and nitrogenase, critical for digestion of wood and supplementation of the host's nitrogen-deficient diet. T. turnerae is closely related to the free-living marine polysaccharide degrading bacterium Saccharophagus degradans str. 2-40 and to as yet uncultivated endosymbionts with which it coexists in shipworm cells. Like S. degradans, the T. turnerae genome encodes a large number of enzymes predicted to be involved in complex polysaccharide degradation (>100). However, unlike S. degradans, which degrades a broad spectrum (>10 classes) of complex plant, fungal and algal polysaccharides, T. turnerae primarily encodes enzymes associated with deconstruction of terrestrial woody plant material. Also unlike S. degradans and many other eubacteria, T. turnerae dedicates a large proportion of its genome to genes predicted to function in secondary metabolism. Despite its intracellular niche, the T. turnerae genome lacks many features associated with obligate intracellular existence (e.g. reduced genome size, reduced %G+C, loss of genes of core metabolism) and displays evidence of adaptations common to free-living bacteria (e.g. defense against bacteriophage infection). These results suggest that T. turnerae is likely a facultative intracellular ensosymbiont whose niche presently includes, or recently included, free-living existence. As such, the T. turnerae genome provides insights into the range of genomic adaptations associated with intracellular endosymbiosis as well as enzymatic mechanisms relevant to the recycling of plant materials in marine environments and the production of cellulose-derived biofuels.
AB - Here we report the complete genome sequence of Teredinibacter turnerae T7901. T. turnerae is a marine gamma proteobacterium that occurs as an intracellular endosymbiont in the gills of wood-boring marine bivalves of the family Teredinidae (shipworms). This species is the sole cultivated member of an endosymbiotic consortium thought to provide the host with enzymes, including cellulases and nitrogenase, critical for digestion of wood and supplementation of the host's nitrogen-deficient diet. T. turnerae is closely related to the free-living marine polysaccharide degrading bacterium Saccharophagus degradans str. 2-40 and to as yet uncultivated endosymbionts with which it coexists in shipworm cells. Like S. degradans, the T. turnerae genome encodes a large number of enzymes predicted to be involved in complex polysaccharide degradation (>100). However, unlike S. degradans, which degrades a broad spectrum (>10 classes) of complex plant, fungal and algal polysaccharides, T. turnerae primarily encodes enzymes associated with deconstruction of terrestrial woody plant material. Also unlike S. degradans and many other eubacteria, T. turnerae dedicates a large proportion of its genome to genes predicted to function in secondary metabolism. Despite its intracellular niche, the T. turnerae genome lacks many features associated with obligate intracellular existence (e.g. reduced genome size, reduced %G+C, loss of genes of core metabolism) and displays evidence of adaptations common to free-living bacteria (e.g. defense against bacteriophage infection). These results suggest that T. turnerae is likely a facultative intracellular ensosymbiont whose niche presently includes, or recently included, free-living existence. As such, the T. turnerae genome provides insights into the range of genomic adaptations associated with intracellular endosymbiosis as well as enzymatic mechanisms relevant to the recycling of plant materials in marine environments and the production of cellulose-derived biofuels.
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U2 - 10.1371/journal.pone.0006085
DO - 10.1371/journal.pone.0006085
M3 - Article
C2 - 19568419
AN - SCOPUS:67749097789
SN - 1932-6203
VL - 4
JO - PloS one
JF - PloS one
IS - 7
M1 - e6085
ER -