Abstract
The goal of the Complex Trait Consortium is to promote the development of resources that can be used to understand, treat and ultimately prevent pervasive human diseases. Existing and proposed mouse resources that are optimized to study the actions of isolated genetic loci on a fixed background are less effective for studying intact polygenic networks and interactions among genes, environments, pathogens and other factors. The Collaborative Cross will provide a common reference panel specifically designed for the integrative analysis of complex systems and will change the way we approach human health and disease.
Original language | English (US) |
---|---|
Pages (from-to) | 1133-1137 |
Number of pages | 5 |
Journal | Nature genetics |
Volume | 36 |
Issue number | 11 |
DOIs | |
State | Published - Nov 2004 |
ASJC Scopus subject areas
- Genetics
Access to Document
Fingerprint Dive into the research topics of 'The Collaborative Cross, a community resource for the genetic analysis of complex traits'. Together they form a unique fingerprint.
Cite this
- APA
- Standard
- Harvard
- Vancouver
- Author
- BIBTEX
- RIS
The Collaborative Cross, a community resource for the genetic analysis of complex traits. / Churchill, Gary A.; Airey, David C.; Allayee, Hooman; Angel, Joe M.; Attie, Alan D.; Beatty, Jackson; Beavis, Willam D.; Belknap, John K.; Bennett, Beth; Berrettini, Wade; Bleich, Andre; Bogue, Molly; Broman, Karl W.; Buck, Kari J.; Buckler, Ed; Burmeister, Margit; Chesler, Elissa J.; Cheverud, James M.; Clapcote, Steven; Cook, Melloni N.; Cox, Roger D.; Crabbe, John C.; Crusio, Wim E.; Darvasi, Ariel; Deschepper, Christian F.; Doerge, R. W.; Farber, Charles R.; Forejt, Jiri; Gaile, Daniel; Garlow, Steven J.; Geiger, Hartmut; Gershenfeld, Howard; Gordon, Terry; Gu, Jing; Gu, Weikuan; de Haan, Gerald; Hayes, Nancy L.; Heller, Craig; Himmelbauer, Heinz; Hitzemann, Robert; Hunter, Kent; Hsu, Hui Chen; Iraqi, Fuad A.; Ivandic, Boris; Jacob, Howard J.; Jansen, Ritsert C.; Jepsen, Karl J.; Johnson, Dabney K.; Johnson, Thomas E.; Kempermann, Gerd; Kendziorski, Christina; Kotb, Malak; Kooy, R. Frank; Llamas, Bastien; Lammert, Frank; Lassalle, Jean Michel; Lowenstein, Pedro R.; Lu, Lu; Lusis, Aldons; Manly, Kenneth F.; Marcucio, Ralph; Matthews, Doug; Medrano, Juan F.; Miller, Darla R.; Mittleman, Guy; Mock, Beverly A.; Mogil, Jeffrey S.; Montagutelli, Xavier; Morahan, Grant; Morris, David G.; Mott, Richard; Nadeau, Joseph H.; Nagase, Hiroki; Nowakowski, Richard S.; O'Hara, Bruce F.; Osadchuk, Alexander V.; Page, Grier P.; Paigen, Beverly; Paigen, Kenneth; Palmer, Abraham A.; Pan, Huei Ju; Peltonen-Palotie, Leena; Peirce, Jeremy; Pomp, Daniel; Pravenec, Michal; Prows, Daniel R.; Qi, Zonghua; Reeves, Roger H.; Roder, John; Rosen, Glenn D.; Schadt, Eric E.; Schalkwyk, Leonard C.; Seltzer, Ze'ev; Shimomura, Kazuhiro; Shou, Siming; Sillanpää, Mikko J.; Siracusa, Linda D.; Snoeck, Hans Willem; Spearow, Jimmy L.; Svenson, Karen; Tarantino, Lisa M.; Threadgill, David; Toth, Linda A.; Valdar, William; Pardo-Manuel de Villena, Fernando; Warden, Craig; Whatley, Steve; Williams, Robert W.; Wiltshire, Tom; Yi, Nengjun; Zhang, Dabao; Zhang, Min; Zou, Fei.
In: Nature genetics, Vol. 36, No. 11, 11.2004, p. 1133-1137.Research output: Contribution to journal › Review article › peer-review
}
TY - JOUR
T1 - The Collaborative Cross, a community resource for the genetic analysis of complex traits
AU - Churchill, Gary A.
AU - Airey, David C.
AU - Allayee, Hooman
AU - Angel, Joe M.
AU - Attie, Alan D.
AU - Beatty, Jackson
AU - Beavis, Willam D.
AU - Belknap, John K.
AU - Bennett, Beth
AU - Berrettini, Wade
AU - Bleich, Andre
AU - Bogue, Molly
AU - Broman, Karl W.
AU - Buck, Kari J.
AU - Buckler, Ed
AU - Burmeister, Margit
AU - Chesler, Elissa J.
AU - Cheverud, James M.
AU - Clapcote, Steven
AU - Cook, Melloni N.
AU - Cox, Roger D.
AU - Crabbe, John C.
AU - Crusio, Wim E.
AU - Darvasi, Ariel
AU - Deschepper, Christian F.
AU - Doerge, R. W.
AU - Farber, Charles R.
AU - Forejt, Jiri
AU - Gaile, Daniel
AU - Garlow, Steven J.
AU - Geiger, Hartmut
AU - Gershenfeld, Howard
AU - Gordon, Terry
AU - Gu, Jing
AU - Gu, Weikuan
AU - de Haan, Gerald
AU - Hayes, Nancy L.
AU - Heller, Craig
AU - Himmelbauer, Heinz
AU - Hitzemann, Robert
AU - Hunter, Kent
AU - Hsu, Hui Chen
AU - Iraqi, Fuad A.
AU - Ivandic, Boris
AU - Jacob, Howard J.
AU - Jansen, Ritsert C.
AU - Jepsen, Karl J.
AU - Johnson, Dabney K.
AU - Johnson, Thomas E.
AU - Kempermann, Gerd
AU - Kendziorski, Christina
AU - Kotb, Malak
AU - Kooy, R. Frank
AU - Llamas, Bastien
AU - Lammert, Frank
AU - Lassalle, Jean Michel
AU - Lowenstein, Pedro R.
AU - Lu, Lu
AU - Lusis, Aldons
AU - Manly, Kenneth F.
AU - Marcucio, Ralph
AU - Matthews, Doug
AU - Medrano, Juan F.
AU - Miller, Darla R.
AU - Mittleman, Guy
AU - Mock, Beverly A.
AU - Mogil, Jeffrey S.
AU - Montagutelli, Xavier
AU - Morahan, Grant
AU - Morris, David G.
AU - Mott, Richard
AU - Nadeau, Joseph H.
AU - Nagase, Hiroki
AU - Nowakowski, Richard S.
AU - O'Hara, Bruce F.
AU - Osadchuk, Alexander V.
AU - Page, Grier P.
AU - Paigen, Beverly
AU - Paigen, Kenneth
AU - Palmer, Abraham A.
AU - Pan, Huei Ju
AU - Peltonen-Palotie, Leena
AU - Peirce, Jeremy
AU - Pomp, Daniel
AU - Pravenec, Michal
AU - Prows, Daniel R.
AU - Qi, Zonghua
AU - Reeves, Roger H.
AU - Roder, John
AU - Rosen, Glenn D.
AU - Schadt, Eric E.
AU - Schalkwyk, Leonard C.
AU - Seltzer, Ze'ev
AU - Shimomura, Kazuhiro
AU - Shou, Siming
AU - Sillanpää, Mikko J.
AU - Siracusa, Linda D.
AU - Snoeck, Hans Willem
AU - Spearow, Jimmy L.
AU - Svenson, Karen
AU - Tarantino, Lisa M.
AU - Threadgill, David
AU - Toth, Linda A.
AU - Valdar, William
AU - Pardo-Manuel de Villena, Fernando
AU - Warden, Craig
AU - Whatley, Steve
AU - Williams, Robert W.
AU - Wiltshire, Tom
AU - Yi, Nengjun
AU - Zhang, Dabao
AU - Zhang, Min
AU - Zou, Fei
N1 - Copyright: Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2004/11
Y1 - 2004/11
N2 - The goal of the Complex Trait Consortium is to promote the development of resources that can be used to understand, treat and ultimately prevent pervasive human diseases. Existing and proposed mouse resources that are optimized to study the actions of isolated genetic loci on a fixed background are less effective for studying intact polygenic networks and interactions among genes, environments, pathogens and other factors. The Collaborative Cross will provide a common reference panel specifically designed for the integrative analysis of complex systems and will change the way we approach human health and disease.
AB - The goal of the Complex Trait Consortium is to promote the development of resources that can be used to understand, treat and ultimately prevent pervasive human diseases. Existing and proposed mouse resources that are optimized to study the actions of isolated genetic loci on a fixed background are less effective for studying intact polygenic networks and interactions among genes, environments, pathogens and other factors. The Collaborative Cross will provide a common reference panel specifically designed for the integrative analysis of complex systems and will change the way we approach human health and disease.
UR - http://www.scopus.com/inward/record.url?scp=14644441018&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=14644441018&partnerID=8YFLogxK
U2 - 10.1038/ng1104-1133
DO - 10.1038/ng1104-1133
M3 - Review article
C2 - 15514660
AN - SCOPUS:14644441018
VL - 36
SP - 1133
EP - 1137
JO - Nature Genetics
JF - Nature Genetics
SN - 1061-4036
IS - 11
ER -