The clinical significance of Raynaud's syndrome

J. M. Porter, E. J. Bardana, G. M. Baur, D. H. Wesche, R. H. Andrasch, Josef Rosch

Research output: Contribution to journalArticle

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Abstract

This study was performed to determine the frequency of occurrence of associated autoimmune disease in a group of patients presenting with Raynaud's symptoms. A consecutive group of 100 patients presenting with Raynaud's syndrome underwent detailed prospective clinical and immunologic evaluation. Magnification hand arteriography was performed in certain patients. Based on current diagnostic criteria, the following autoimmune diseases were diagnosed or were suspected strongly: Raynaud's syndrome with scleroderma or CRST - 28 patients; Raynaud's syndrome with lupus erythematosus - 10 patients; Raynaud's syndrome with miscellaneous autoimmune disease - 43 patients; Raynaud's syndrome without diagnosable autoimmune disease - 19 patients. Fourteen of the 19 patients in the latter group had isolated serologic abnormalities. Arteriography showed combined organic arterial obstruction and vasospasm of the palmar and digital arteries in all patients. Patients with severe Raynaud's symptoms had more extensive arterial obstruction than did patients with mild or moderate Raynaud's symptoms. These results suggest that all patients with Raynaud's syndrome should be regarded as at high risk for having an associated autoimmune disease.

Original languageEnglish (US)
Pages (from-to)756-764
Number of pages9
JournalSurgery
Volume80
Issue number6
StatePublished - 1976
Externally publishedYes

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Autoimmune Diseases
Angiography
Hand
Arteries

ASJC Scopus subject areas

  • Surgery

Cite this

Porter, J. M., Bardana, E. J., Baur, G. M., Wesche, D. H., Andrasch, R. H., & Rosch, J. (1976). The clinical significance of Raynaud's syndrome. Surgery, 80(6), 756-764.

The clinical significance of Raynaud's syndrome. / Porter, J. M.; Bardana, E. J.; Baur, G. M.; Wesche, D. H.; Andrasch, R. H.; Rosch, Josef.

In: Surgery, Vol. 80, No. 6, 1976, p. 756-764.

Research output: Contribution to journalArticle

Porter, JM, Bardana, EJ, Baur, GM, Wesche, DH, Andrasch, RH & Rosch, J 1976, 'The clinical significance of Raynaud's syndrome', Surgery, vol. 80, no. 6, pp. 756-764.
Porter JM, Bardana EJ, Baur GM, Wesche DH, Andrasch RH, Rosch J. The clinical significance of Raynaud's syndrome. Surgery. 1976;80(6):756-764.
Porter, J. M. ; Bardana, E. J. ; Baur, G. M. ; Wesche, D. H. ; Andrasch, R. H. ; Rosch, Josef. / The clinical significance of Raynaud's syndrome. In: Surgery. 1976 ; Vol. 80, No. 6. pp. 756-764.
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