The Changing Liver Transplant Recipient: From Hepatitis C to Nonalcoholic Steatohepatitis and Alcohol

Ross Vyhmeister, C. Kristian Enestvedt

Research output: Contribution to journalReview articlepeer-review

Abstract

Hepatitis C virus has historically been the leading indication for liver transplant, followed by nonalcoholic steatohepatitis (NASH) and alcoholic liver disease. Severe alcoholic hepatitis has become a growing indication for liver transplant, and overall alcohol use rates continue to increase in the United States. Rates of obesity and NASH in the United States continue to increase and are expected to place increasing demand on liver transplant infrastructure. In the current absence of robust pharmacologic therapy for NASH, the use of bariatric procedures and surgeries is being explored, as are other innovative approaches to curtail this upward trend.

Original languageEnglish (US)
Pages (from-to)137-155
Number of pages19
JournalClinics in liver disease
Volume25
Issue number1
DOIs
StatePublished - Feb 2021

Keywords

  • Alcoholic liver disease
  • Hepatitis C
  • Indications
  • Liver transplant
  • Nonalcoholic steatohepatitis

ASJC Scopus subject areas

  • Hepatology

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