Abstract
Sepsis-induced myocardial dysfunction has traditionally been thought of as principally affecting systolic heart function. One of the primary reasons for this concept is that systolic dysfunction is relatively easy to conceptualize, visualize, and measure. With the advent of preload-independent measurements for diastolic function, both measurement and conceptual difficulties are being resolved, and a new realm of evidence is beginning to emerge regarding the aberrations that are found during cardiac relaxation in sepsis. A recent article in Critical Care brings this issue into sharper focus.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 132 |
| Number of pages | 1 |
| Journal | Critical Care |
| Volume | 13 |
| Issue number | 2 |
| State | Published - 2009 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Medicine(all)
Cite this
The cardiac force-frequency relationship and frequency-dependent acceleration of relaxation are impaired in lipopolysaccharide-treated rats : is the phospholamban-SERCA axis a therapeutic target? / Heitner, Stephen; Hollenberg, Steven M.
In: Critical Care, Vol. 13, No. 2, 2009, p. 132.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The cardiac force-frequency relationship and frequency-dependent acceleration of relaxation are impaired in lipopolysaccharide-treated rats
T2 - is the phospholamban-SERCA axis a therapeutic target?
AU - Heitner, Stephen
AU - Hollenberg, Steven M.
PY - 2009
Y1 - 2009
N2 - Sepsis-induced myocardial dysfunction has traditionally been thought of as principally affecting systolic heart function. One of the primary reasons for this concept is that systolic dysfunction is relatively easy to conceptualize, visualize, and measure. With the advent of preload-independent measurements for diastolic function, both measurement and conceptual difficulties are being resolved, and a new realm of evidence is beginning to emerge regarding the aberrations that are found during cardiac relaxation in sepsis. A recent article in Critical Care brings this issue into sharper focus.
AB - Sepsis-induced myocardial dysfunction has traditionally been thought of as principally affecting systolic heart function. One of the primary reasons for this concept is that systolic dysfunction is relatively easy to conceptualize, visualize, and measure. With the advent of preload-independent measurements for diastolic function, both measurement and conceptual difficulties are being resolved, and a new realm of evidence is beginning to emerge regarding the aberrations that are found during cardiac relaxation in sepsis. A recent article in Critical Care brings this issue into sharper focus.
UR - http://www.scopus.com/inward/record.url?scp=69849086446&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=69849086446&partnerID=8YFLogxK
M3 - Article
C2 - 19439042
AN - SCOPUS:69849086446
VL - 13
SP - 132
JO - Critical Care
JF - Critical Care
SN - 1364-8535
IS - 2
ER -