The association of blood component use ratios with the survival of massively transfused trauma patients with and without severe brain injury

Philip C. Spinella, Charles E. Wade, Lorne H. Blackbourne, Matthew A. Borgman, Lee A. Zarzabal, Fei Du, Jeremy G. Perkins, Marc Maegele, Martin Schreiber, John R. Hess, Kenneth M. Jastrow, Ernest A. Gonzalez, John B. Holcomb, Rosemary Kozar, Trauma Outcomes Group The Trauma Outcomes Group

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

Background: The effect of blood component ratios on the survival of patients with traumatic brain injury (TBI) has not been studied. Methods: A database of patients transfused in the first 24 hours after admission for injury from 22 Level I trauma centers over an 18-month period was queried to find patients who (1) met different definitions of massive transfusion (5 units red blood cell [RBC] in 6 hours vs. 10 units RBC in 24 hours), (2) received high or low ratios of platelets or plasma to RBC units (

Original languageEnglish (US)
JournalJournal of Trauma - Injury, Infection and Critical Care
Volume71
Issue number2 SUPPL. 3
DOIs
StatePublished - Aug 2011
Externally publishedYes

Fingerprint

Brain Injuries
Erythrocytes
Survival
Wounds and Injuries
Trauma Centers
Blood Platelets
Databases
Traumatic Brain Injury

Keywords

  • Mortality
  • Plasma
  • Platelets
  • Red Blood Cell
  • Transfusion

ASJC Scopus subject areas

  • Surgery
  • Critical Care and Intensive Care Medicine

Cite this

Spinella, P. C., Wade, C. E., Blackbourne, L. H., Borgman, M. A., Zarzabal, L. A., Du, F., ... The Trauma Outcomes Group, T. O. G. (2011). The association of blood component use ratios with the survival of massively transfused trauma patients with and without severe brain injury. Journal of Trauma - Injury, Infection and Critical Care, 71(2 SUPPL. 3). https://doi.org/10.1097/TA.0b013e318227ef2d

The association of blood component use ratios with the survival of massively transfused trauma patients with and without severe brain injury. / Spinella, Philip C.; Wade, Charles E.; Blackbourne, Lorne H.; Borgman, Matthew A.; Zarzabal, Lee A.; Du, Fei; Perkins, Jeremy G.; Maegele, Marc; Schreiber, Martin; Hess, John R.; Jastrow, Kenneth M.; Gonzalez, Ernest A.; Holcomb, John B.; Kozar, Rosemary; The Trauma Outcomes Group, Trauma Outcomes Group.

In: Journal of Trauma - Injury, Infection and Critical Care, Vol. 71, No. 2 SUPPL. 3, 08.2011.

Research output: Contribution to journalArticle

Spinella, PC, Wade, CE, Blackbourne, LH, Borgman, MA, Zarzabal, LA, Du, F, Perkins, JG, Maegele, M, Schreiber, M, Hess, JR, Jastrow, KM, Gonzalez, EA, Holcomb, JB, Kozar, R & The Trauma Outcomes Group, TOG 2011, 'The association of blood component use ratios with the survival of massively transfused trauma patients with and without severe brain injury', Journal of Trauma - Injury, Infection and Critical Care, vol. 71, no. 2 SUPPL. 3. https://doi.org/10.1097/TA.0b013e318227ef2d
Spinella, Philip C. ; Wade, Charles E. ; Blackbourne, Lorne H. ; Borgman, Matthew A. ; Zarzabal, Lee A. ; Du, Fei ; Perkins, Jeremy G. ; Maegele, Marc ; Schreiber, Martin ; Hess, John R. ; Jastrow, Kenneth M. ; Gonzalez, Ernest A. ; Holcomb, John B. ; Kozar, Rosemary ; The Trauma Outcomes Group, Trauma Outcomes Group. / The association of blood component use ratios with the survival of massively transfused trauma patients with and without severe brain injury. In: Journal of Trauma - Injury, Infection and Critical Care. 2011 ; Vol. 71, No. 2 SUPPL. 3.
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