The association between abnormal birth history and growth in children with CKD

Larry A. Greenbaum, Alvaro Muñoz, Michael F. Schneider, Frederick J. Kaskel, David J. Askenazi, Randall Jenkins, Hilary Hotchkiss, Marva Moxey-Mims, Susan L. Furth, Bradley A. Warady

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Background and objectives: Poor linear growth is a well described complication of chronic kidney disease (CKD). This study evaluated whether abnormal birth history defined by low birth weight (LBW; 2, 21% had a glomerular diagnosis, and 52% had CKD for ≥90% of their lifetime. Results: A high prevalence of LBW (17%), SGA (14%), prematurity (12%), and ICU after delivery (40%) was observed. Multivariate analyses demonstrated a negative effect of LBW (-0.43 ± 0.14; P <0.01 for height and -0.37 ± 0.16; P = 0.02 for weight) and of SGA (-0.29 ± 0.16; P = 0.07 for height and -0.41 ± 0.19; P = 0.03 for weight) on current height and weight. In children with glomerular versus nonglomerular diagnoses, the effect of SGA (-1.08 versus -0.18; P = 0.029) on attained weight was more pronounced in children with a glomerular diagnosis. Conclusions: LBW and SGA are novel risk factors for short stature and lower weight percentiles in children with mild to moderate CKD independent of kidney function.

Original languageEnglish (US)
Pages (from-to)14-21
Number of pages8
JournalClinical Journal of the American Society of Nephrology
Volume6
Issue number1
DOIs
StatePublished - Jan 1 2011
Externally publishedYes

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Reproductive History
Chronic Renal Insufficiency
Weights and Measures
Growth
Low Birth Weight Infant
Multivariate Analysis
Kidney

ASJC Scopus subject areas

  • Nephrology
  • Transplantation
  • Epidemiology
  • Critical Care and Intensive Care Medicine

Cite this

Greenbaum, L. A., Muñoz, A., Schneider, M. F., Kaskel, F. J., Askenazi, D. J., Jenkins, R., ... Warady, B. A. (2011). The association between abnormal birth history and growth in children with CKD. Clinical Journal of the American Society of Nephrology, 6(1), 14-21. https://doi.org/10.2215/CJN.08481109

The association between abnormal birth history and growth in children with CKD. / Greenbaum, Larry A.; Muñoz, Alvaro; Schneider, Michael F.; Kaskel, Frederick J.; Askenazi, David J.; Jenkins, Randall; Hotchkiss, Hilary; Moxey-Mims, Marva; Furth, Susan L.; Warady, Bradley A.

In: Clinical Journal of the American Society of Nephrology, Vol. 6, No. 1, 01.01.2011, p. 14-21.

Research output: Contribution to journalArticle

Greenbaum, LA, Muñoz, A, Schneider, MF, Kaskel, FJ, Askenazi, DJ, Jenkins, R, Hotchkiss, H, Moxey-Mims, M, Furth, SL & Warady, BA 2011, 'The association between abnormal birth history and growth in children with CKD', Clinical Journal of the American Society of Nephrology, vol. 6, no. 1, pp. 14-21. https://doi.org/10.2215/CJN.08481109
Greenbaum, Larry A. ; Muñoz, Alvaro ; Schneider, Michael F. ; Kaskel, Frederick J. ; Askenazi, David J. ; Jenkins, Randall ; Hotchkiss, Hilary ; Moxey-Mims, Marva ; Furth, Susan L. ; Warady, Bradley A. / The association between abnormal birth history and growth in children with CKD. In: Clinical Journal of the American Society of Nephrology. 2011 ; Vol. 6, No. 1. pp. 14-21.
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