The amphibian (rana esculenta) brain progesterone receptor: Relationship to plasma steroids and vitellogenic cycle during the gonadal recovery phase

Giulia Guerriero, Charles E. Roselli, Gaetano Ciarcia

Research output: Chapter in Book/Report/Conference proceedingConference contribution

10 Scopus citations

Abstract

We report the presence of a progesterone receptor (PR) in the brain of the female amphibian Rana esculenta and changes in the levels of this PR during the gonadal recovery phase in relation to different circulating steroid levels and steroid treatment. The highest level of the PR in the nuclear brain extract corresponded to a low level of plasma progesterone and occurred when vitellogenin synthesis was at a minimum. The lowest level was found during follicular growth, concomitant with increased plasma 17β-estradiol and progesterone levels. The PR levels were significantly higher in ovariectomized female R. esculenta than in intact and sham-operated female frogs. Treatment with 17β-estradiol and progesterone downregulated the frog brain PR, indicating that a possible progesterone-receptor interaction is involved in the modulation of vitellogenin.

Original languageEnglish (US)
Title of host publicationTrends in Comparative Endocrinology and Neurobiology
PublisherBlackwell Publishing Inc.
Pages407-409
Number of pages3
ISBN (Print)9781573316712
DOIs
StatePublished - Apr 2009

Publication series

NameAnnals of the New York Academy of Sciences
Volume1163
ISSN (Print)0077-8923
ISSN (Electronic)1749-6632

Keywords

  • Brain
  • Progesterone receptor
  • Rana esculenta
  • Reproduction
  • Vitellogenesis

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

Fingerprint Dive into the research topics of 'The amphibian (rana esculenta) brain progesterone receptor: Relationship to plasma steroids and vitellogenic cycle during the gonadal recovery phase'. Together they form a unique fingerprint.

  • Cite this

    Guerriero, G., Roselli, C. E., & Ciarcia, G. (2009). The amphibian (rana esculenta) brain progesterone receptor: Relationship to plasma steroids and vitellogenic cycle during the gonadal recovery phase. In Trends in Comparative Endocrinology and Neurobiology (pp. 407-409). (Annals of the New York Academy of Sciences; Vol. 1163). Blackwell Publishing Inc.. https://doi.org/10.1111/j.1749-6632.2009.04438.x