Testing percutaneous arterial closure devices: An animal model

Rui Fang Ni, Pawanrat Kranokpiraksa, Dusan Pavcnik, Hideaki Kakizawa, Barry Uchida, Frederick Keller, Josef Rosch

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The ovine superficial femoral artery was used for testing the efficacy of percutaneous arterial closure devices (PACDs) in their developmental stage. Two topical devices containing chitostan, one staple-mediated PACD and a porcine small intestinal submucosa plug, were tested by follow-up angiography in 37 sheep. Absence or presence of bleeding and time to bleeding cessation were the main criteria for evaluation of PAVD efficacy. The results of these tests directed modification of individual PACDs and improved their efficacy.

Original languageEnglish (US)
Pages (from-to)313-316
Number of pages4
JournalCardioVascular and Interventional Radiology
Volume32
Issue number2
DOIs
StatePublished - Mar 2009

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Animal Models
Equipment and Supplies
Sheep
Bleeding Time
Femoral Artery
Angiography
Swine
Hemorrhage

Keywords

  • Animal model
  • Experimental device
  • Hemostasis
  • Percutaneous arterial procedures

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Testing percutaneous arterial closure devices : An animal model. / Ni, Rui Fang; Kranokpiraksa, Pawanrat; Pavcnik, Dusan; Kakizawa, Hideaki; Uchida, Barry; Keller, Frederick; Rosch, Josef.

In: CardioVascular and Interventional Radiology, Vol. 32, No. 2, 03.2009, p. 313-316.

Research output: Contribution to journalArticle

Ni, Rui Fang ; Kranokpiraksa, Pawanrat ; Pavcnik, Dusan ; Kakizawa, Hideaki ; Uchida, Barry ; Keller, Frederick ; Rosch, Josef. / Testing percutaneous arterial closure devices : An animal model. In: CardioVascular and Interventional Radiology. 2009 ; Vol. 32, No. 2. pp. 313-316.
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