Testing percutaneous arterial closure devices: An animal model

Rui Fang Ni; Pawanrat Kranokpiraksa; Dusan Pavcnik; Hideaki Kakizawa; Barry T. Uchida; Frederick S. Keller; Josef Rösch

doi:10.1007/s00270-008-9426-1

Testing percutaneous arterial closure devices: An animal model

Rui Fang Ni, Pawanrat Kranokpiraksa, Dusan Pavcnik, Hideaki Kakizawa, Barry T. Uchida, Frederick S. Keller, Josef Rösch

Dotter Interventional Institute

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

The ovine superficial femoral artery was used for testing the efficacy of percutaneous arterial closure devices (PACDs) in their developmental stage. Two topical devices containing chitostan, one staple-mediated PACD and a porcine small intestinal submucosa plug, were tested by follow-up angiography in 37 sheep. Absence or presence of bleeding and time to bleeding cessation were the main criteria for evaluation of PAVD efficacy. The results of these tests directed modification of individual PACDs and improved their efficacy.

Original language	English (US)
Pages (from-to)	313-316
Number of pages	4
Journal	Cardiovascular and interventional radiology
Volume	32
Issue number	2
DOIs	https://doi.org/10.1007/s00270-008-9426-1
State	Published - Mar 2009

Keywords

Animal model
Experimental device
Hemostasis
Percutaneous arterial procedures

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Cardiology and Cardiovascular Medicine

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abstract = "The ovine superficial femoral artery was used for testing the efficacy of percutaneous arterial closure devices (PACDs) in their developmental stage. Two topical devices containing chitostan, one staple-mediated PACD and a porcine small intestinal submucosa plug, were tested by follow-up angiography in 37 sheep. Absence or presence of bleeding and time to bleeding cessation were the main criteria for evaluation of PAVD efficacy. The results of these tests directed modification of individual PACDs and improved their efficacy.",

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AU - Ni, Rui Fang

AU - Kranokpiraksa, Pawanrat

AU - Pavcnik, Dusan

AU - Kakizawa, Hideaki

AU - Uchida, Barry T.

AU - Keller, Frederick S.

AU - Rösch, Josef

PY - 2009/3

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AB - The ovine superficial femoral artery was used for testing the efficacy of percutaneous arterial closure devices (PACDs) in their developmental stage. Two topical devices containing chitostan, one staple-mediated PACD and a porcine small intestinal submucosa plug, were tested by follow-up angiography in 37 sheep. Absence or presence of bleeding and time to bleeding cessation were the main criteria for evaluation of PAVD efficacy. The results of these tests directed modification of individual PACDs and improved their efficacy.

KW - Animal model

KW - Experimental device

KW - Hemostasis

KW - Percutaneous arterial procedures

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Testing percutaneous arterial closure devices: An animal model

Abstract

Keywords

ASJC Scopus subject areas

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