@article{776a4add23c44750a5de89bcf38af13b,
title = "Testing depth of suppression in childhood intermittent exotropia",
abstract = "A test of suppression was developed to provide a standardized approach to detecting and grading density of suppression in children with intermittent exotropia when manifestly exotropic. This new Office Suppression Test is a three-step procedure to grade suppression on a 4-point scale (from 0 for “negligible suppression” to 3 for “dense suppression”). The test was performed in 57 children 3-13 years of age with intermittent exotropia (distance angle of 16Δ-35Δ, with spontaneous tropia) during enrollment in a randomized trial. Of the 57 children, 51 could complete testing: 28 (55%) had dense suppression, 12 (24%) had moderate suppression, 5 (10%) had mild suppression, and 6 (12%) had negligible suppression. In a subgroup of 20 untreated children, suppression was evaluated again at 8 weeks. There was moderate agreement between suppression scores at baseline and at 8 weeks (weighted κ = 0.65 [95% CI, 0.45-0.84]).",
author = "Hatt, {Sarah R.} and Leske, {David A.} and Holmes, {Jonathan M.} and Henderson, {Robert J.} and Chandler, {Danielle L.} and Morrison, {David G.} and Summers, {Allison I.} and Cotter, {Susan A.}",
note = "Funding Information: Funding/Support: National Eye Institute of National Institutes of Health, Department of Health and Human Services EY011751, EY023198, EY018810 (JMH), and EY024333 (JMH). The funding organization had no role in the design or conduct of this research. Funding Information: The pilot randomized controlled trial ( www.clinicaltrials.gov : NCT03998670) was funded by the National Eye Institute and conducted according to the tenets of the Declaration of Helsinki by the Pediatric Eye Disease Investigator Group (PEDIG). The study protocol and Health Insurance Portability and Accountability Act–compliant informed consent forms were approved by the institutional review boards of participating study centers. A parent or guardian gave written informed consent for each child; written assent was obtained for children ≥7 years of age. Publisher Copyright: {\textcopyright} 2021 American Association for Pediatric Ophthalmology and Strabismus",
year = "2022",
month = feb,
doi = "10.1016/j.jaapos.2021.08.303",
language = "English (US)",
volume = "26",
pages = "36--38.e1",
journal = "Journal of AAPOS",
issn = "1091-8531",
publisher = "Mosby Inc.",
number = "1",
}