Abstract
Objective: The purpose of this study was to assess the long-term outcome of patients with tardive dyskinesia. Method: A group of 122 neuroleptic-treated Hungarian outpatients were assessed for tardive dyskinesia on the Abnormal Involuntary Movement Scale and the Tardive Dyskinesia Rating Scale by the same rater over a 10-year period. Results: Sixty-three of the patients received both 5- and 10-year follow-up assessments and are the subjects of this report. The overall prevalence of tardive dyskinesia in this group changed little over time; it was 30.2% at baseline, 36.5% at 5 years, and 31.7% at 10 years. However, there were changes in the tardive dyskinesia status of individual patients; 11 patients had remissions, and 12 who did not have tardive dyskinesia at the baseline assessment had developed it by the 10-year assessment. These two subgroups did not differ significantly on demographic and drug history variables. Outcome of tardive dyskinesia was not significantly related to neuroleptic treatment or to age. Conclusions: The data of this 10-year follow-up study provide evidence for the long-term stability of tardive dyskinesia and for the feasibility of maintenance neuroleptic therapy for chronic psychotic patients who have tardive dyskinesia.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 836-841 |
| Number of pages | 6 |
| Journal | American Journal of Psychiatry |
| Volume | 151 |
| Issue number | 6 |
| State | Published - Jun 1994 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Psychiatry and Mental health
Cite this
Ten-year outcome of tardive dyskinesia. / Gardos, George; Casey, Daniel; Cole, Jonathan O.; Perenyi, Andras; Kocsis, Edit; Arato, Mihaly; Samson, Jacqueline A.; Conley, Caitlyn.
In: American Journal of Psychiatry, Vol. 151, No. 6, 06.1994, p. 836-841.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ten-year outcome of tardive dyskinesia
AU - Gardos, George
AU - Casey, Daniel
AU - Cole, Jonathan O.
AU - Perenyi, Andras
AU - Kocsis, Edit
AU - Arato, Mihaly
AU - Samson, Jacqueline A.
AU - Conley, Caitlyn
PY - 1994/6
Y1 - 1994/6
N2 - Objective: The purpose of this study was to assess the long-term outcome of patients with tardive dyskinesia. Method: A group of 122 neuroleptic-treated Hungarian outpatients were assessed for tardive dyskinesia on the Abnormal Involuntary Movement Scale and the Tardive Dyskinesia Rating Scale by the same rater over a 10-year period. Results: Sixty-three of the patients received both 5- and 10-year follow-up assessments and are the subjects of this report. The overall prevalence of tardive dyskinesia in this group changed little over time; it was 30.2% at baseline, 36.5% at 5 years, and 31.7% at 10 years. However, there were changes in the tardive dyskinesia status of individual patients; 11 patients had remissions, and 12 who did not have tardive dyskinesia at the baseline assessment had developed it by the 10-year assessment. These two subgroups did not differ significantly on demographic and drug history variables. Outcome of tardive dyskinesia was not significantly related to neuroleptic treatment or to age. Conclusions: The data of this 10-year follow-up study provide evidence for the long-term stability of tardive dyskinesia and for the feasibility of maintenance neuroleptic therapy for chronic psychotic patients who have tardive dyskinesia.
AB - Objective: The purpose of this study was to assess the long-term outcome of patients with tardive dyskinesia. Method: A group of 122 neuroleptic-treated Hungarian outpatients were assessed for tardive dyskinesia on the Abnormal Involuntary Movement Scale and the Tardive Dyskinesia Rating Scale by the same rater over a 10-year period. Results: Sixty-three of the patients received both 5- and 10-year follow-up assessments and are the subjects of this report. The overall prevalence of tardive dyskinesia in this group changed little over time; it was 30.2% at baseline, 36.5% at 5 years, and 31.7% at 10 years. However, there were changes in the tardive dyskinesia status of individual patients; 11 patients had remissions, and 12 who did not have tardive dyskinesia at the baseline assessment had developed it by the 10-year assessment. These two subgroups did not differ significantly on demographic and drug history variables. Outcome of tardive dyskinesia was not significantly related to neuroleptic treatment or to age. Conclusions: The data of this 10-year follow-up study provide evidence for the long-term stability of tardive dyskinesia and for the feasibility of maintenance neuroleptic therapy for chronic psychotic patients who have tardive dyskinesia.
UR - http://www.scopus.com/inward/record.url?scp=0028308428&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028308428&partnerID=8YFLogxK
M3 - Article
C2 - 7910437
AN - SCOPUS:0028308428
VL - 151
SP - 836
EP - 841
JO - American Journal of Psychiatry
JF - American Journal of Psychiatry
SN - 0002-953X
IS - 6
ER -