Ten-year outcome of tardive dyskinesia

George Gardos, Daniel Casey, Jonathan O. Cole, Andras Perenyi, Edit Kocsis, Mihaly Arato, Jacqueline A. Samson, Caitlyn Conley

Research output: Contribution to journalArticle

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Abstract

Objective: The purpose of this study was to assess the long-term outcome of patients with tardive dyskinesia. Method: A group of 122 neuroleptic-treated Hungarian outpatients were assessed for tardive dyskinesia on the Abnormal Involuntary Movement Scale and the Tardive Dyskinesia Rating Scale by the same rater over a 10-year period. Results: Sixty-three of the patients received both 5- and 10-year follow-up assessments and are the subjects of this report. The overall prevalence of tardive dyskinesia in this group changed little over time; it was 30.2% at baseline, 36.5% at 5 years, and 31.7% at 10 years. However, there were changes in the tardive dyskinesia status of individual patients; 11 patients had remissions, and 12 who did not have tardive dyskinesia at the baseline assessment had developed it by the 10-year assessment. These two subgroups did not differ significantly on demographic and drug history variables. Outcome of tardive dyskinesia was not significantly related to neuroleptic treatment or to age. Conclusions: The data of this 10-year follow-up study provide evidence for the long-term stability of tardive dyskinesia and for the feasibility of maintenance neuroleptic therapy for chronic psychotic patients who have tardive dyskinesia.

Original languageEnglish (US)
Pages (from-to)836-841
Number of pages6
JournalAmerican Journal of Psychiatry
Volume151
Issue number6
StatePublished - Jun 1994
Externally publishedYes

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Antipsychotic Agents
Tardive Dyskinesia
Outpatients
History
Maintenance
Demography
Therapeutics
Pharmaceutical Preparations
Abnormal Involuntary Movement Scale

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Gardos, G., Casey, D., Cole, J. O., Perenyi, A., Kocsis, E., Arato, M., ... Conley, C. (1994). Ten-year outcome of tardive dyskinesia. American Journal of Psychiatry, 151(6), 836-841.

Ten-year outcome of tardive dyskinesia. / Gardos, George; Casey, Daniel; Cole, Jonathan O.; Perenyi, Andras; Kocsis, Edit; Arato, Mihaly; Samson, Jacqueline A.; Conley, Caitlyn.

In: American Journal of Psychiatry, Vol. 151, No. 6, 06.1994, p. 836-841.

Research output: Contribution to journalArticle

Gardos, G, Casey, D, Cole, JO, Perenyi, A, Kocsis, E, Arato, M, Samson, JA & Conley, C 1994, 'Ten-year outcome of tardive dyskinesia', American Journal of Psychiatry, vol. 151, no. 6, pp. 836-841.
Gardos G, Casey D, Cole JO, Perenyi A, Kocsis E, Arato M et al. Ten-year outcome of tardive dyskinesia. American Journal of Psychiatry. 1994 Jun;151(6):836-841.
Gardos, George ; Casey, Daniel ; Cole, Jonathan O. ; Perenyi, Andras ; Kocsis, Edit ; Arato, Mihaly ; Samson, Jacqueline A. ; Conley, Caitlyn. / Ten-year outcome of tardive dyskinesia. In: American Journal of Psychiatry. 1994 ; Vol. 151, No. 6. pp. 836-841.
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