Temporal daily associations between pain and sleep in adolescents with chronic pain versus healthy adolescents

Amy Holley, Tonya M. Palermo, Stacy De La Motte, Rongwei (Rochelle) Fu

Research output: Contribution to journalArticle

77 Citations (Scopus)

Abstract

Adolescents with chronic pain frequently report sleep disturbances, particularly short sleep duration, night wakings, and poor sleep quality. Prior research has been limited by assessment of subjectively reported sleep only and lack of data on daily relationships between sleep and pain. The current study utilized multilevel modeling to compare daily associations between sleep and pain in adolescents with chronic pain and healthy adolescents. Ninety-seven adolescents (n = 39 chronic pain; n = 58 healthy) aged 12-18, 70.1% female participated. Adolescents completed pain diary ratings (0-10 NRS) and actigraphic sleep monitoring for 10 days. Actigraphic sleep variables (duration, efficiency, WASO) and self-reported sleep quality were tested as predictors of next-day pain, and daytime pain was tested as a predictor of sleep that night. Effects of age, gender, study group, and depressive symptoms on daily associations between sleep and pain were also tested. Multivariate analyses revealed that nighttime sleep (p <.001) and minutes awake after sleep onset (WASO) (p <.05) predicted next-day pain, with longer sleep duration and higher WASO associated with higher pain. Contrary to hypotheses, neither nighttime sleep quality nor sleep efficiency predicted pain the following day. The interaction between nighttime sleep efficiency and study group was significant, with adolescents with pain showing stronger associations between sleep efficiency and next-day pain than healthy participants (p = .05). Contrary to hypotheses, daytime pain did not predict nighttime sleep. Daily associations between pain and sleep suggest that further work is needed to identify specific adolescent sleep behaviors (e.g., compensatory sleep behaviors) that may be targeted in interventions.

Original languageEnglish (US)
Pages (from-to)220-225
Number of pages6
JournalPain
Volume151
Issue number1
DOIs
StatePublished - Oct 2010

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Chronic Pain
Sleep
Pain
Adolescent Behavior
Polysomnography

Keywords

  • Actigraphy
  • Adolescents
  • Chronic pain
  • Multilevel-modeling
  • Pain
  • Sleep

ASJC Scopus subject areas

  • Clinical Neurology
  • Anesthesiology and Pain Medicine
  • Neurology
  • Pharmacology

Cite this

Temporal daily associations between pain and sleep in adolescents with chronic pain versus healthy adolescents. / Holley, Amy; Palermo, Tonya M.; Motte, Stacy De La; Fu, Rongwei (Rochelle).

In: Pain, Vol. 151, No. 1, 10.2010, p. 220-225.

Research output: Contribution to journalArticle

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