Targeting mTOR signaling overcomes acquired resistance to combined BRAF and MEK inhibition in BRAF-mutant melanoma

Beike Wang, Wei Zhang, Gao Zhang, Lawrence Kwong, Hezhe Lu, Jiufeng Tan, Norah Sadek, Min Xiao, Jie Zhang, Marilyne Labrie, Sergio Randell, Aurelie Beroard, Eric Sugarman, Vito W. Rebecca, Zhi Wei, Yiling Lu, Gordon B. Mills, Jeffrey Field, Jessie Villanueva, Xiaowei XuMeenhard Herlyn, Wei Guo

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Medicine & Life Sciences