Tackling formalin-fixed, paraffin-embedded tumor tissue with next-generation sequencing

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Abstract

Most tumor samples available for clinical genotyping are formalin-fixed and paraffin-embedded (FFPE), but there has been relatively little published on the suitability of such samples for next-generation sequencing approaches. A new study by Wagle and colleagues shows that a combination of hybridization-capture and deep sequencing yields high-quality data from FFPE specimens.

Original languageEnglish (US)
Pages (from-to)23-24
Number of pages2
JournalCancer discovery
Volume2
Issue number1
DOIs
StatePublished - Jan 1 2012

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ASJC Scopus subject areas

  • Oncology

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